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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PABPC1L All Species: 37.88
Human Site: S585 Identified Species: 64.1
UniProt: Q4VXU2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4VXU2 NP_001118228.1 614 68392 S585 E L L L M L E S P E S L H A K
Chimpanzee Pan troglodytes XP_514668 614 68388 S585 E L L L M L E S P E S L H A K
Rhesus Macaque Macaca mulatta Q7JGR2 382 43298 G363 K A V D E M N G R V V G S K P
Dog Lupus familis XP_534430 611 67706 S582 E L L L M L E S P E S L N A K
Cat Felis silvestris
Mouse Mus musculus P29341 636 70624 S599 E L L H M L E S P E S L R S K
Rat Rattus norvegicus Q9EPH8 636 70682 S599 E L L H M L E S P E S L R S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509272 636 70681 S599 E L L H M L E S P E S L R S K
Chicken Gallus gallus XP_417367 632 70180 S598 E L L L L L E S P E S L H S K
Frog Xenopus laevis Q98SP8 629 70685 S596 E L L H M L E S P E S L H S K
Zebra Danio Brachydanio rerio NP_956133 620 69010 S594 E L L H M L E S P E S L H A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P21187 634 69907 D609 E L L H M I E D Q E A L K A K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q05196 668 73191 S631 E I L H L L E S P E A L K A K
Baker's Yeast Sacchar. cerevisiae P04147 577 64326 L551 P L L E S D E L F E Q H Y K E
Red Bread Mold Neurospora crassa Q7S6N6 764 82299 D714 E L I N L F E D D N A L N V K
Conservation
Percent
Protein Identity: 100 99.8 36.3 87.3 N.A. 67.9 68 N.A. 68 75 72.8 70.1 N.A. 54.5 N.A. N.A. N.A.
Protein Similarity: 100 100 47.3 92.5 N.A. 79.7 79.7 N.A. 79.5 84 82.8 82.2 N.A. 68.6 N.A. N.A. N.A.
P-Site Identity: 100 100 0 93.3 N.A. 80 80 N.A. 80 86.6 86.6 93.3 N.A. 60 N.A. N.A. N.A.
P-Site Similarity: 100 100 20 100 N.A. 86.6 86.6 N.A. 86.6 100 93.3 93.3 N.A. 73.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 41.1 43.1 41.1
Protein Similarity: N.A. N.A. N.A. 57.1 60.4 54.7
P-Site Identity: N.A. N.A. N.A. 66.6 26.6 33.3
P-Site Similarity: N.A. N.A. N.A. 86.6 40 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 22 0 0 43 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 8 0 15 8 0 0 0 0 0 0 % D
% Glu: 86 0 0 8 8 0 93 0 0 86 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % G
% His: 0 0 0 50 0 0 0 0 0 0 0 8 36 0 0 % H
% Ile: 0 8 8 0 0 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 0 0 0 0 0 0 15 15 86 % K
% Leu: 0 86 86 29 22 72 0 8 0 0 0 86 0 0 0 % L
% Met: 0 0 0 0 65 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 8 0 0 8 0 0 15 0 0 % N
% Pro: 8 0 0 0 0 0 0 0 72 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 0 22 0 0 % R
% Ser: 0 0 0 0 8 0 0 72 0 0 65 0 8 36 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 8 0 0 0 0 0 0 8 8 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _