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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PABPC1L All Species: 11.21
Human Site: Y421 Identified Species: 18.97
UniProt: Q4VXU2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4VXU2 NP_001118228.1 614 68392 Y421 P P A Q A A Y Y G C G P V T P
Chimpanzee Pan troglodytes XP_514668 614 68388 Y421 P P A Q A A Y Y G C G P V T P
Rhesus Macaque Macaca mulatta Q7JGR2 382 43298 N205 F T N V F V K N I G D D I D D
Dog Lupus familis XP_534430 611 67706 Y421 P P A Q A A Y Y A S G L P M Q
Cat Felis silvestris
Mouse Mus musculus P29341 636 70624 A421 P Q T Q N R A A Y Y P P S Q I
Rat Rattus norvegicus Q9EPH8 636 70682 A421 P Q T Q N R A A Y Y P P S Q I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509272 636 70681 A421 P Q T Q N R A A Y Y P A S Q I
Chicken Gallus gallus XP_417367 632 70180 Y421 P Q T R A A F Y S P S P V V P
Frog Xenopus laevis Q98SP8 629 70685 S421 P P N R T F Y S P N P V A P V
Zebra Danio Brachydanio rerio NP_956133 620 69010 A421 Q V R S F Y N A V P N L R P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P21187 634 69907 Q415 N Q R F F G S Q V A T Q M R N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q05196 668 73191 H456 H H P M F I G H N G Q G L V P
Baker's Yeast Sacchar. cerevisiae P04147 577 64326 L392 Q I V A G K P L Y V A I A Q R
Red Bread Mold Neurospora crassa Q7S6N6 764 82299 P513 Q P G F M P A P G G R G V P F
Conservation
Percent
Protein Identity: 100 99.8 36.3 87.3 N.A. 67.9 68 N.A. 68 75 72.8 70.1 N.A. 54.5 N.A. N.A. N.A.
Protein Similarity: 100 100 47.3 92.5 N.A. 79.7 79.7 N.A. 79.5 84 82.8 82.2 N.A. 68.6 N.A. N.A. N.A.
P-Site Identity: 100 100 0 60 N.A. 20 20 N.A. 13.3 46.6 20 0 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 60 N.A. 20 20 N.A. 13.3 60 26.6 0 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 41.1 43.1 41.1
Protein Similarity: N.A. N.A. N.A. 57.1 60.4 54.7
P-Site Identity: N.A. N.A. N.A. 6.6 0 20
P-Site Similarity: N.A. N.A. N.A. 20 0 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 22 8 29 29 29 29 8 8 8 8 15 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 8 0 8 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 15 29 8 8 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 8 0 8 8 8 0 22 22 22 15 0 0 0 % G
% His: 8 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 8 0 0 8 0 0 8 8 0 22 % I
% Lys: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 8 0 0 0 15 8 0 0 % L
% Met: 0 0 0 8 8 0 0 0 0 0 0 0 8 8 0 % M
% Asn: 8 0 15 0 22 0 8 8 8 8 8 0 0 0 8 % N
% Pro: 58 36 8 0 0 8 8 8 8 15 29 36 8 22 29 % P
% Gln: 22 36 0 43 0 0 0 8 0 0 8 8 0 29 8 % Q
% Arg: 0 0 15 15 0 22 0 0 0 0 8 0 8 8 8 % R
% Ser: 0 0 0 8 0 0 8 8 8 8 8 0 22 0 0 % S
% Thr: 0 8 29 0 8 0 0 0 0 0 8 0 0 15 0 % T
% Val: 0 8 8 8 0 8 0 0 15 8 0 8 29 15 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 29 29 29 22 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _