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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NHEDC1
All Species:
8.79
Human Site:
S458
Identified Species:
27.62
UniProt:
Q4ZJI4
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4ZJI4
NP_001094344.1
515
56054
S458
A
L
E
T
A
R
V
S
A
P
H
L
E
P
Y
Chimpanzee
Pan troglodytes
XP_001169851
515
56017
S458
A
L
E
T
A
R
V
S
A
P
H
L
E
P
Y
Rhesus Macaque
Macaca mulatta
XP_001110182
511
55485
V457
L
V
L
E
T
A
R
V
S
A
P
H
L
E
P
Dog
Lupus familis
XP_535675
512
55648
S456
A
L
E
T
A
R
I
S
A
P
H
L
E
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0X2
565
61939
M509
A
L
E
T
A
R
V
M
A
P
H
L
E
G
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516421
234
24801
P180
G
F
F
I
R
Y
F
P
S
P
D
Q
E
R
L
Chicken
Gallus gallus
XP_426332
543
57700
Q479
L
D
T
A
R
S
H
Q
D
E
Q
L
E
K
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799202
601
64264
R507
A
L
D
T
A
R
D
R
G
S
E
E
E
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
91.6
71.2
N.A.
61.4
N.A.
N.A.
28.7
52.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
37.9
Protein Similarity:
100
99.4
95.7
85.2
N.A.
74.6
N.A.
N.A.
36.8
68.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
55.7
P-Site Identity:
100
100
0
86.6
N.A.
86.6
N.A.
N.A.
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
13.3
93.3
N.A.
86.6
N.A.
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
63
0
0
13
63
13
0
0
50
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
13
0
0
0
13
0
13
0
13
0
0
0
0
% D
% Glu:
0
0
50
13
0
0
0
0
0
13
13
13
88
13
13
% E
% Phe:
0
13
13
0
0
0
13
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
0
13
0
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
13
0
0
0
50
13
0
0
0
% H
% Ile:
0
0
0
13
0
0
13
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% K
% Leu:
25
63
13
0
0
0
0
0
0
0
0
63
13
13
13
% L
% Met:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
13
0
63
13
0
0
25
13
% P
% Gln:
0
0
0
0
0
0
0
13
0
0
13
13
0
0
0
% Q
% Arg:
0
0
0
0
25
63
13
13
0
0
0
0
0
13
0
% R
% Ser:
0
0
0
0
0
13
0
38
25
13
0
0
0
13
0
% S
% Thr:
0
0
13
63
13
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
13
0
0
0
0
38
13
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
63
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _