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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NHEDC1
All Species:
4.55
Human Site:
Y500
Identified Species:
14.29
UniProt:
Q4ZJI4
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4ZJI4
NP_001094344.1
515
56054
Y500
P
K
M
L
T
R
H
Y
D
P
S
K
I
K
L
Chimpanzee
Pan troglodytes
XP_001169851
515
56017
Y500
P
K
M
L
T
R
H
Y
D
P
S
K
I
K
L
Rhesus Macaque
Macaca mulatta
XP_001110182
511
55485
R497
I
L
G
P
K
L
L
R
R
H
Y
D
P
S
K
Dog
Lupus familis
XP_535675
512
55648
H497
G
P
K
I
L
T
R
H
D
P
S
K
I
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0X2
565
61939
E551
P
K
I
L
E
Q
S
E
V
T
F
P
L
K
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516421
234
24801
L220
G
S
G
G
L
C
T
L
V
L
A
F
L
A
G
Chicken
Gallus gallus
XP_426332
543
57700
Q521
P
R
L
L
Q
K
A
Q
T
K
H
E
E
N
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799202
601
64264
P551
T
R
L
L
R
C
A
P
P
P
N
Q
T
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
91.6
71.2
N.A.
61.4
N.A.
N.A.
28.7
52.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
37.9
Protein Similarity:
100
99.4
95.7
85.2
N.A.
74.6
N.A.
N.A.
36.8
68.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
55.7
P-Site Identity:
100
100
0
33.3
N.A.
26.6
N.A.
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
0
53.3
N.A.
53.3
N.A.
N.A.
13.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
25
0
0
0
13
0
0
13
0
% A
% Cys:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
38
0
0
13
0
0
0
% D
% Glu:
0
0
0
0
13
0
0
13
0
0
0
13
13
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
13
13
0
0
0
% F
% Gly:
25
0
25
13
0
0
0
0
0
0
0
0
0
0
13
% G
% His:
0
0
0
0
0
0
25
13
0
13
13
0
0
0
0
% H
% Ile:
13
0
13
13
0
0
0
0
0
0
0
0
38
0
0
% I
% Lys:
0
38
13
0
13
13
0
0
0
13
0
38
0
38
13
% K
% Leu:
0
13
25
63
25
13
13
13
0
13
0
0
25
0
25
% L
% Met:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
13
0
0
25
0
% N
% Pro:
50
13
0
13
0
0
0
13
13
50
0
13
13
0
0
% P
% Gln:
0
0
0
0
13
13
0
13
0
0
0
13
0
0
0
% Q
% Arg:
0
25
0
0
13
25
13
13
13
0
0
0
0
0
0
% R
% Ser:
0
13
0
0
0
0
13
0
0
0
38
0
0
25
13
% S
% Thr:
13
0
0
0
25
13
13
0
13
13
0
0
13
0
0
% T
% Val:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
25
0
0
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _