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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAN2 All Species: 18.48
Human Site: S1162 Identified Species: 31.28
UniProt: Q504Q3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q504Q3 NP_001120932.1 1202 135368 S1162 K N G T E P E S F H K V L K G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001114958 1201 135190 S1161 K N G T E P E S F H K V L K G
Dog Lupus familis XP_531635 1201 135014 S1161 K N G T E P E S F H K V L K G
Cat Felis silvestris
Mouse Mus musculus Q8BGF7 1200 135235 S1161 K N G T E P E S F H K V L K G
Rat Rattus norvegicus Q6IE70 1205 135608 S1162 K N G A E P E S F H K V L K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513697 979 109930 S942 Y R K Y L E L S R H G R E P E
Chicken Gallus gallus Q5F450 1197 134844 D1157 Q G G S E P D D F R K V L K A
Frog Xenopus laevis NP_001086001 639 71850 I602 S D E A T G K I N L G R L I Q
Zebra Danio Brachydanio rerio XP_001920000 1198 135304 L1147 D A R T A L Q L Y R K Y L E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610427 1241 138949 A1201 T H D S I E D A R T T L Q L Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P53015 1131 127156 E1089 E Q G L L G S E M R R I Y T I
Sea Urchin Strong. purpuratus XP_001194902 1068 120683 K1031 Y T A M R L Y K K Y L V L K A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53010 1115 127021 H1073 H D S I E D A H T A L I L Y K
Red Bread Mold Neurospora crassa P0C581 1236 136082 V1081 A N G S F H D V L E A L Y K K
Conservation
Percent
Protein Identity: 100 N.A. 99.2 97.4 N.A. 96 94.6 N.A. 60.1 85.7 43.7 74.1 N.A. 42.2 N.A. 26.7 44.4
Protein Similarity: 100 N.A. 99.7 99.1 N.A. 97.9 96.9 N.A. 68.3 92.7 48.8 86.1 N.A. 59.3 N.A. 45 61.3
P-Site Identity: 100 N.A. 100 100 N.A. 100 93.3 N.A. 13.3 53.3 6.6 20 N.A. 0 N.A. 6.6 20
P-Site Similarity: 100 N.A. 100 100 N.A. 100 93.3 N.A. 13.3 73.3 20 40 N.A. 33.3 N.A. 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.3 22.1
Protein Similarity: N.A. N.A. N.A. N.A. 41.6 41.5
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 20
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 15 8 0 8 8 0 8 8 0 0 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 15 8 0 0 8 22 8 0 0 0 0 0 0 0 % D
% Glu: 8 0 8 0 50 15 36 8 0 8 0 0 8 8 8 % E
% Phe: 0 0 0 0 8 0 0 0 43 0 0 0 0 0 0 % F
% Gly: 0 8 58 0 0 15 0 0 0 0 15 0 0 0 36 % G
% His: 8 8 0 0 0 8 0 8 0 43 0 0 0 0 0 % H
% Ile: 0 0 0 8 8 0 0 8 0 0 0 15 0 8 8 % I
% Lys: 36 0 8 0 0 0 8 8 8 0 50 0 0 58 15 % K
% Leu: 0 0 0 8 15 15 8 8 8 8 15 15 72 8 8 % L
% Met: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 43 0 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 43 0 0 0 0 0 0 0 8 0 % P
% Gln: 8 8 0 0 0 0 8 0 0 0 0 0 8 0 8 % Q
% Arg: 0 8 8 0 8 0 0 0 15 22 8 15 0 0 0 % R
% Ser: 8 0 8 22 0 0 8 43 0 0 0 0 0 0 0 % S
% Thr: 8 8 0 36 8 0 0 0 8 8 8 0 0 8 0 % T
% Val: 0 0 0 0 0 0 0 8 0 0 0 50 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 15 0 0 8 0 0 8 0 8 8 0 8 15 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _