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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAN2 All Species: 19.7
Human Site: T196 Identified Species: 33.33
UniProt: Q504Q3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q504Q3 NP_001120932.1 1202 135368 T196 T Q K Y A V E T P G V T I M R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001114958 1201 135190 T196 T Q K Y A V E T P G V T I M R
Dog Lupus familis XP_531635 1201 135014 T196 T Q K Y A V E T P G V T I M R
Cat Felis silvestris
Mouse Mus musculus Q8BGF7 1200 135235 T196 T Q K Y A V E T P G V T I M R
Rat Rattus norvegicus Q6IE70 1205 135608 T196 T Q K Y A V E T P G V T I M R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513697 979 109930 F72 Q V H V D P A F L R F I P T Y
Chicken Gallus gallus Q5F450 1197 134844 V196 T Q K Y T V E V P G I T I M R
Frog Xenopus laevis NP_001086001 639 71850
Zebra Danio Brachydanio rerio XP_001920000 1198 135304 V196 T Q K F T V E V P G V A I M R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610427 1241 138949 A184 T R I E H V G A G G C T V L R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P53015 1131 127156 C189 E T I H T L D C H Q D Q V L D
Sea Urchin Strong. purpuratus XP_001194902 1068 120683 S161 L V E V D L G S G V Q T V T H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53010 1115 127021 L183 R Q T G T V D L L D P T S N R
Red Bread Mold Neurospora crassa P0C581 1236 136082 G185 K K Q W Q A H G A F I N D L D
Conservation
Percent
Protein Identity: 100 N.A. 99.2 97.4 N.A. 96 94.6 N.A. 60.1 85.7 43.7 74.1 N.A. 42.2 N.A. 26.7 44.4
Protein Similarity: 100 N.A. 99.7 99.1 N.A. 97.9 96.9 N.A. 68.3 92.7 48.8 86.1 N.A. 59.3 N.A. 45 61.3
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 0 80 0 73.3 N.A. 33.3 N.A. 0 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 0 86.6 0 80 N.A. 53.3 N.A. 33.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.3 22.1
Protein Similarity: N.A. N.A. N.A. N.A. 41.6 41.5
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 36 8 8 8 8 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 15 0 15 0 0 8 8 0 8 0 15 % D
% Glu: 8 0 8 8 0 0 50 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 8 0 8 8 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 15 8 15 58 0 0 0 0 0 % G
% His: 0 0 8 8 8 0 8 0 8 0 0 0 0 0 8 % H
% Ile: 0 0 15 0 0 0 0 0 0 0 15 8 50 0 0 % I
% Lys: 8 8 50 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 0 0 15 0 8 15 0 0 0 0 22 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % N
% Pro: 0 0 0 0 0 8 0 0 50 0 8 0 8 0 0 % P
% Gln: 8 58 8 0 8 0 0 0 0 8 8 8 0 0 0 % Q
% Arg: 8 8 0 0 0 0 0 0 0 8 0 0 0 0 65 % R
% Ser: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % S
% Thr: 58 8 8 0 29 0 0 36 0 0 0 65 0 15 0 % T
% Val: 0 15 0 15 0 65 0 15 0 8 43 0 22 0 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 43 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _