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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAN2 All Species: 32.12
Human Site: Y1042 Identified Species: 54.36
UniProt: Q504Q3 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q504Q3 NP_001120932.1 1202 135368 Y1042 V V D Y L T Q Y S G I K P G D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001114958 1201 135190 Y1041 V V D Y L T Q Y S G I K P G D
Dog Lupus familis XP_531635 1201 135014 Y1041 V V D Y L T Q Y S G I K P G D
Cat Felis silvestris
Mouse Mus musculus Q8BGF7 1200 135235 Y1041 V V D Y L T Q Y S G I K P G D
Rat Rattus norvegicus Q6IE70 1205 135608 Y1042 V V D Y L T Q Y S G I K P G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513697 979 109930 S844 D L D A K I S S K H L T T L K
Chicken Gallus gallus Q5F450 1197 134844 Y1037 V V D Y L T Q Y S G I K P G D
Frog Xenopus laevis NP_001086001 639 71850 K504 G L E D F D F K H Y N K T L F
Zebra Danio Brachydanio rerio XP_001920000 1198 135304 Y1043 V V D Y L T Q Y S G I K P G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610427 1241 138949 F1103 V V D Y L T Q F S G I K P G D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P53015 1131 127156 F969 V V D Y L T K F S G I V K A D
Sea Urchin Strong. purpuratus XP_001194902 1068 120683 L933 S G I K P G D L D A T I S S K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53010 1115 127021 Y975 I E D Y L T R Y S G I L P G D
Red Bread Mold Neurospora crassa P0C581 1236 136082 W960 I V D Y L T E W S G I T P T D
Conservation
Percent
Protein Identity: 100 N.A. 99.2 97.4 N.A. 96 94.6 N.A. 60.1 85.7 43.7 74.1 N.A. 42.2 N.A. 26.7 44.4
Protein Similarity: 100 N.A. 99.7 99.1 N.A. 97.9 96.9 N.A. 68.3 92.7 48.8 86.1 N.A. 59.3 N.A. 45 61.3
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 6.6 100 6.6 100 N.A. 93.3 N.A. 66.6 0
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 20 100 20 100 N.A. 100 N.A. 80 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.3 22.1
Protein Similarity: N.A. N.A. N.A. N.A. 41.6 41.5
P-Site Identity: N.A. N.A. N.A. N.A. 73.3 66.6
P-Site Similarity: N.A. N.A. N.A. N.A. 86.6 86.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 8 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 86 8 0 8 8 0 8 0 0 0 0 0 79 % D
% Glu: 0 8 8 0 0 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 8 0 8 15 0 0 0 0 0 0 8 % F
% Gly: 8 8 0 0 0 8 0 0 0 79 0 0 0 65 0 % G
% His: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % H
% Ile: 15 0 8 0 0 8 0 0 0 0 79 8 0 0 0 % I
% Lys: 0 0 0 8 8 0 8 8 8 0 0 65 8 0 15 % K
% Leu: 0 15 0 0 79 0 0 8 0 0 8 8 0 15 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 0 0 72 0 0 % P
% Gln: 0 0 0 0 0 0 58 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 8 0 0 0 0 0 8 8 79 0 0 0 8 8 0 % S
% Thr: 0 0 0 0 0 79 0 0 0 0 8 15 15 8 0 % T
% Val: 65 72 0 0 0 0 0 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 79 0 0 0 58 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _