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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC39A12
All Species:
13.64
Human Site:
S196
Identified Species:
30
UniProt:
Q504Y0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q504Y0
NP_001138667.1
691
76680
S196
Q
K
K
S
G
I
V
S
S
E
G
A
N
E
S
Chimpanzee
Pan troglodytes
XP_001153573
691
76663
S196
Q
K
K
S
G
I
V
S
S
E
G
A
N
E
S
Rhesus Macaque
Macaca mulatta
XP_001092136
691
76579
S196
Q
K
K
S
G
I
V
S
S
E
G
A
N
E
N
Dog
Lupus familis
XP_848350
688
75996
S196
Q
E
K
S
G
I
L
S
S
D
G
A
D
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q5FWH7
689
76197
G195
Q
R
E
S
G
I
Q
G
S
N
G
A
D
E
K
Rat
Rattus norvegicus
A0JPN2
656
71103
G174
L
E
E
A
E
E
A
G
V
S
R
S
P
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509347
667
73284
R202
E
W
R
S
G
I
S
R
S
E
G
A
D
A
N
Chicken
Gallus gallus
Q5ZI20
366
39255
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PEH9
847
95085
P283
H
H
H
K
H
P
H
P
H
L
H
A
P
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793407
1036
112759
M318
G
G
L
F
V
P
C
M
S
E
G
V
Y
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M647
469
50564
V16
L
V
P
I
L
V
L
V
L
F
L
D
L
C
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.9
83.5
N.A.
77.8
32.2
N.A.
56.1
20.5
N.A.
25
N.A.
N.A.
N.A.
N.A.
22.7
Protein Similarity:
100
99.5
98.5
90.4
N.A.
84.5
51.5
N.A.
69.7
32.7
N.A.
42.6
N.A.
N.A.
N.A.
N.A.
37.4
P-Site Identity:
100
100
93.3
66.6
N.A.
53.3
0
N.A.
46.6
0
N.A.
20
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
73.3
26.6
N.A.
73.3
0
N.A.
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
0
0
0
0
64
0
10
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
10
28
10
0
% D
% Glu:
10
19
19
0
10
10
0
0
0
46
0
0
0
55
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
10
10
0
0
55
0
0
19
0
0
64
0
0
10
0
% G
% His:
10
10
10
0
10
0
10
0
10
0
10
0
0
0
0
% H
% Ile:
0
0
0
10
0
55
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
28
37
10
0
0
0
0
0
0
0
0
0
0
19
% K
% Leu:
19
0
10
0
10
0
19
0
10
10
10
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
28
0
28
% N
% Pro:
0
0
10
0
0
19
0
10
0
0
0
0
19
0
0
% P
% Gln:
46
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
10
0
0
0
0
10
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
55
0
0
10
37
64
10
0
10
0
0
28
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
10
10
28
10
10
0
0
10
0
0
10
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _