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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC39A12 All Species: 21.82
Human Site: S197 Identified Species: 48
UniProt: Q504Y0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q504Y0 NP_001138667.1 691 76680 S197 K K S G I V S S E G A N E S T
Chimpanzee Pan troglodytes XP_001153573 691 76663 S197 K K S G I V S S E G A N E S T
Rhesus Macaque Macaca mulatta XP_001092136 691 76579 S197 K K S G I V S S E G A N E N T
Dog Lupus familis XP_848350 688 75996 S197 E K S G I L S S D G A D E N T
Cat Felis silvestris
Mouse Mus musculus Q5FWH7 689 76197 S196 R E S G I Q G S N G A D E K T
Rat Rattus norvegicus A0JPN2 656 71103 V175 E E A E E A G V S R S P G L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509347 667 73284 S203 W R S G I S R S E G A D A N T
Chicken Gallus gallus Q5ZI20 366 39255
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6PEH9 847 95085 H284 H H K H P H P H L H A P E S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793407 1036 112759 S319 G L F V P C M S E G V Y D K T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M647 469 50564 L17 V P I L V L V L F L D L C V E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 96.9 83.5 N.A. 77.8 32.2 N.A. 56.1 20.5 N.A. 25 N.A. N.A. N.A. N.A. 22.7
Protein Similarity: 100 99.5 98.5 90.4 N.A. 84.5 51.5 N.A. 69.7 32.7 N.A. 42.6 N.A. N.A. N.A. N.A. 37.4
P-Site Identity: 100 100 93.3 66.6 N.A. 53.3 0 N.A. 53.3 0 N.A. 20 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 100 100 N.A. 73.3 26.6 N.A. 73.3 0 N.A. 20 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 20.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 10 0 0 0 0 64 0 10 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 10 28 10 0 0 % D
% Glu: 19 19 0 10 10 0 0 0 46 0 0 0 55 0 10 % E
% Phe: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 10 0 0 55 0 0 19 0 0 64 0 0 10 0 0 % G
% His: 10 10 0 10 0 10 0 10 0 10 0 0 0 0 0 % H
% Ile: 0 0 10 0 55 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 28 37 10 0 0 0 0 0 0 0 0 0 0 19 0 % K
% Leu: 0 10 0 10 0 19 0 10 10 10 0 10 0 10 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 28 0 28 0 % N
% Pro: 0 10 0 0 19 0 10 0 0 0 0 19 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 10 0 0 0 0 10 0 0 10 0 0 0 0 0 % R
% Ser: 0 0 55 0 0 10 37 64 10 0 10 0 0 28 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64 % T
% Val: 10 0 0 10 10 28 10 10 0 0 10 0 0 10 19 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _