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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC39A12 All Species: 16.67
Human Site: S513 Identified Species: 36.67
UniProt: Q504Y0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q504Y0 NP_001138667.1 691 76680 S513 A S T I Q L K S P E D S Q A A
Chimpanzee Pan troglodytes XP_001153573 691 76663 S513 A S T I Q L K S P E D S Q A A
Rhesus Macaque Macaca mulatta XP_001092136 691 76579 S513 A S T I Q L K S P E D S Q A A
Dog Lupus familis XP_848350 688 75996 S510 A S T L Q L K S P E D S Q A A
Cat Felis silvestris
Mouse Mus musculus Q5FWH7 689 76197 G511 I S T I Q L K G P E D S Q T T
Rat Rattus norvegicus A0JPN2 656 71103 S478 S K Q P H E S S R S D L V T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509347 667 73284 S489 M P E S D K R S P E D S E P V
Chicken Gallus gallus Q5ZI20 366 39255 E198 A G K S Q R A E K N S T Q C N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6PEH9 847 95085 G660 H G H G H G H G H G H G H G H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793407 1036 112759 A449 E S K S E L T A N E A K A F E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M647 469 50564 I302 K S D S G T E I T S D G K S D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 96.9 83.5 N.A. 77.8 32.2 N.A. 56.1 20.5 N.A. 25 N.A. N.A. N.A. N.A. 22.7
Protein Similarity: 100 99.5 98.5 90.4 N.A. 84.5 51.5 N.A. 69.7 32.7 N.A. 42.6 N.A. N.A. N.A. N.A. 37.4
P-Site Identity: 100 100 100 93.3 N.A. 73.3 13.3 N.A. 33.3 20 N.A. 0 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 73.3 20 N.A. 46.6 26.6 N.A. 0 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 20.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 46 0 0 0 0 0 10 10 0 0 10 0 10 37 37 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 10 0 10 0 0 0 0 0 73 0 0 0 10 % D
% Glu: 10 0 10 0 10 10 10 10 0 64 0 0 10 0 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 19 0 10 10 10 0 19 0 10 0 19 0 10 0 % G
% His: 10 0 10 0 19 0 10 0 10 0 10 0 10 0 10 % H
% Ile: 10 0 0 37 0 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 10 10 19 0 0 10 46 0 10 0 0 10 10 0 0 % K
% Leu: 0 0 0 10 0 55 0 0 0 0 0 10 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 10 % N
% Pro: 0 10 0 10 0 0 0 0 55 0 0 0 0 10 0 % P
% Gln: 0 0 10 0 55 0 0 0 0 0 0 0 55 0 0 % Q
% Arg: 0 0 0 0 0 10 10 0 10 0 0 0 0 0 0 % R
% Ser: 10 64 0 37 0 0 10 55 0 19 10 55 0 10 0 % S
% Thr: 0 0 46 0 0 10 10 0 10 0 0 10 0 19 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _