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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC39A12
All Species:
20
Human Site:
S517
Identified Species:
44
UniProt:
Q504Y0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q504Y0
NP_001138667.1
691
76680
S517
Q
L
K
S
P
E
D
S
Q
A
A
E
M
P
I
Chimpanzee
Pan troglodytes
XP_001153573
691
76663
S517
Q
L
K
S
P
E
D
S
Q
A
A
E
M
P
I
Rhesus Macaque
Macaca mulatta
XP_001092136
691
76579
S517
Q
L
K
S
P
E
D
S
Q
A
A
E
M
P
I
Dog
Lupus familis
XP_848350
688
75996
S514
Q
L
K
S
P
E
D
S
Q
A
A
E
I
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5FWH7
689
76197
S515
Q
L
K
G
P
E
D
S
Q
T
T
V
L
P
I
Rat
Rattus norvegicus
A0JPN2
656
71103
L482
H
E
S
S
R
S
D
L
V
T
E
E
T
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509347
667
73284
S493
D
K
R
S
P
E
D
S
E
P
V
R
D
S
A
Chicken
Gallus gallus
Q5ZI20
366
39255
T202
Q
R
A
E
K
N
S
T
Q
C
N
G
S
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PEH9
847
95085
G664
H
G
H
G
H
G
H
G
H
G
H
S
H
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793407
1036
112759
K859
E
L
T
A
N
E
A
K
A
F
E
T
E
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M647
469
50564
G306
G
T
E
I
T
S
D
G
K
S
D
K
P
E
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.9
83.5
N.A.
77.8
32.2
N.A.
56.1
20.5
N.A.
25
N.A.
N.A.
N.A.
N.A.
22.7
Protein Similarity:
100
99.5
98.5
90.4
N.A.
84.5
51.5
N.A.
69.7
32.7
N.A.
42.6
N.A.
N.A.
N.A.
N.A.
37.4
P-Site Identity:
100
100
100
86.6
N.A.
66.6
26.6
N.A.
33.3
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
73.3
26.6
N.A.
46.6
26.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
10
0
10
37
37
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
73
0
0
0
10
0
10
0
0
% D
% Glu:
10
10
10
10
0
64
0
0
10
0
19
46
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
10
10
0
19
0
10
0
19
0
10
0
10
0
0
19
% G
% His:
19
0
10
0
10
0
10
0
10
0
10
0
10
10
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
37
% I
% Lys:
0
10
46
0
10
0
0
10
10
0
0
10
0
0
0
% K
% Leu:
0
55
0
0
0
0
0
10
0
0
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% M
% Asn:
0
0
0
0
10
10
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
55
0
0
0
0
10
0
0
10
55
10
% P
% Gln:
55
0
0
0
0
0
0
0
55
0
0
0
0
0
10
% Q
% Arg:
0
10
10
0
10
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
10
55
0
19
10
55
0
10
0
10
10
19
0
% S
% Thr:
0
10
10
0
10
0
0
10
0
19
10
10
10
10
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _