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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC39A12
All Species:
10
Human Site:
Y288
Identified Species:
22
UniProt:
Q504Y0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q504Y0
NP_001138667.1
691
76680
Y288
I
I
T
H
D
Q
D
Y
S
N
F
S
S
S
M
Chimpanzee
Pan troglodytes
XP_001153573
691
76663
Y288
I
I
T
R
D
Q
D
Y
S
N
F
S
S
S
M
Rhesus Macaque
Macaca mulatta
XP_001092136
691
76579
Y288
I
I
T
P
D
Q
D
Y
S
N
F
S
S
S
M
Dog
Lupus familis
XP_848350
688
75996
G287
N
L
T
I
Y
D
W
G
S
N
L
S
V
S
M
Cat
Felis silvestris
Mouse
Mus musculus
Q5FWH7
689
76197
P288
E
E
H
S
L
R
D
P
K
T
S
T
A
M
D
Rat
Rattus norvegicus
A0JPN2
656
71103
H263
N
H
Q
D
S
E
L
H
A
T
H
N
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509347
667
73284
R290
K
K
K
L
I
V
G
R
E
C
A
Y
L
L
F
Chicken
Gallus gallus
Q5ZI20
366
39255
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PEH9
847
95085
S396
L
L
H
Q
Y
G
L
S
S
D
S
L
I
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793407
1036
112759
E639
F
G
V
I
T
E
E
E
F
A
H
M
L
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M647
469
50564
G104
E
S
S
S
T
L
T
G
F
A
L
W
L
N
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.9
83.5
N.A.
77.8
32.2
N.A.
56.1
20.5
N.A.
25
N.A.
N.A.
N.A.
N.A.
22.7
Protein Similarity:
100
99.5
98.5
90.4
N.A.
84.5
51.5
N.A.
69.7
32.7
N.A.
42.6
N.A.
N.A.
N.A.
N.A.
37.4
P-Site Identity:
100
93.3
93.3
40
N.A.
6.6
13.3
N.A.
0
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
93.3
46.6
N.A.
26.6
40
N.A.
0
0
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
19
10
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
10
28
10
37
0
0
10
0
0
0
0
19
% D
% Glu:
19
10
0
0
0
19
10
10
10
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
19
0
28
0
0
0
10
% F
% Gly:
0
10
0
0
0
10
10
19
0
0
0
0
0
0
0
% G
% His:
0
10
19
10
0
0
0
10
0
0
19
0
0
0
0
% H
% Ile:
28
28
0
19
10
0
0
0
0
0
0
0
10
10
0
% I
% Lys:
10
10
10
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
10
19
0
10
10
10
19
0
0
0
19
10
28
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
37
% M
% Asn:
19
0
0
0
0
0
0
0
0
37
0
10
0
10
0
% N
% Pro:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
10
% P
% Gln:
0
0
10
10
0
28
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
10
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
19
10
0
0
10
46
0
19
37
37
55
10
% S
% Thr:
0
0
37
0
19
0
10
0
0
19
0
10
0
0
0
% T
% Val:
0
0
10
0
0
10
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
19
0
0
28
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _