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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCWPW2
All Species:
4.24
Human Site:
S246
Identified Species:
23.33
UniProt:
Q504Y3
Number Species:
4
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q504Y3
NP_001035522.1
356
41376
S246
R
K
A
I
L
K
C
S
F
E
N
V
Y
S
D
Chimpanzee
Pan troglodytes
XP_516340
356
41342
S246
R
K
A
I
L
K
C
S
F
E
N
V
C
S
D
Rhesus Macaque
Macaca mulatta
XP_001095109
356
41078
A246
R
K
A
I
L
K
C
A
F
E
N
V
C
S
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
XP_002727152
457
51913
L347
G
D
G
A
N
C
V
L
F
Q
L
T
Q
C
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507860
341
39323
E230
E
I
H
N
C
Y
F
E
S
A
C
S
D
G
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
93.8
N.A.
N.A.
N.A.
38.5
N.A.
58.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.3
95.7
N.A.
N.A.
N.A.
53.6
N.A.
71.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
N.A.
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
N.A.
N.A.
N.A.
20
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
60
20
0
0
0
20
0
20
0
0
0
0
0
% A
% Cys:
0
0
0
0
20
20
60
0
0
0
20
0
40
20
0
% C
% Asp:
0
20
0
0
0
0
0
0
0
0
0
0
20
0
60
% D
% Glu:
20
0
0
0
0
0
0
20
0
60
0
0
0
0
20
% E
% Phe:
0
0
0
0
0
0
20
0
80
0
0
0
0
0
0
% F
% Gly:
20
0
20
0
0
0
0
0
0
0
0
0
0
20
0
% G
% His:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
20
0
60
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
60
0
0
0
60
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
60
0
0
20
0
0
20
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
20
20
0
0
0
0
0
60
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
20
0
0
20
0
0
% Q
% Arg:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
40
20
0
0
20
0
60
20
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% T
% Val:
0
0
0
0
0
0
20
0
0
0
0
60
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
20
0
0
0
0
0
0
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _