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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPC2
All Species:
13.64
Human Site:
S349
Identified Species:
27.27
UniProt:
Q52LR7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q52LR7
NP_056445.3
807
91095
S349
K
A
E
A
L
I
T
S
Q
Q
P
T
P
E
T
Chimpanzee
Pan troglodytes
XP_526096
815
91684
S357
K
A
E
A
L
I
T
S
Q
Q
P
T
P
E
T
Rhesus Macaque
Macaca mulatta
XP_001118113
806
91202
S348
K
A
E
A
L
I
T
S
Q
Q
P
T
P
E
T
Dog
Lupus familis
XP_533350
788
88605
S330
K
A
E
A
L
I
T
S
Q
Q
P
T
P
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0I4
808
90941
P349
K
A
E
A
G
I
A
P
Q
Q
P
T
P
E
T
Rat
Rattus norvegicus
NP_001102051
808
90800
P349
K
A
E
A
V
L
A
P
P
Q
P
T
P
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509590
778
87501
P327
P
Q
Q
P
T
T
E
P
L
P
V
I
N
K
S
Chicken
Gallus gallus
XP_422154
784
88610
A349
K
M
E
C
V
V
T
A
Q
Q
P
S
A
E
P
Frog
Xenopus laevis
Q66JA8
804
90630
P349
K
A
D
I
L
V
T
P
L
P
Q
A
N
S
E
Zebra Danio
Brachydanio rerio
NP_957369
751
84595
L324
H
K
I
G
P
K
H
L
H
P
F
P
V
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397232
868
96064
R341
S
L
E
D
N
G
V
R
S
G
T
G
S
G
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192895
443
51775
P16
R
A
P
D
P
A
K
P
M
P
I
Y
T
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
94.1
93.5
N.A.
96.9
96.4
N.A.
86.1
91.5
84.3
60.3
N.A.
N.A.
35.7
N.A.
31.3
Protein Similarity:
100
94.2
95.2
95
N.A.
98.1
98.1
N.A.
89.9
93.6
90.9
72.8
N.A.
N.A.
51.5
N.A.
40.8
P-Site Identity:
100
100
100
100
N.A.
80
66.6
N.A.
0
46.6
26.6
0
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
20
73.3
40
6.6
N.A.
N.A.
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
67
0
50
0
9
17
9
0
0
0
9
9
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
17
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
67
0
0
0
9
0
0
0
0
0
0
59
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
9
9
9
0
0
0
9
0
9
0
9
9
% G
% His:
9
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
0
42
0
0
0
0
9
9
0
0
0
% I
% Lys:
67
9
0
0
0
9
9
0
0
0
0
0
0
17
0
% K
% Leu:
0
9
0
0
42
9
0
9
17
0
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
17
0
0
% N
% Pro:
9
0
9
9
17
0
0
42
9
34
59
9
50
0
17
% P
% Gln:
0
9
9
0
0
0
0
0
50
59
9
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
0
34
9
0
0
9
9
9
9
% S
% Thr:
0
0
0
0
9
9
50
0
0
0
9
50
9
9
50
% T
% Val:
0
0
0
0
17
17
9
0
0
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _