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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPC2
All Species:
32.12
Human Site:
S545
Identified Species:
64.24
UniProt:
Q52LR7
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q52LR7
NP_056445.3
807
91095
S545
S
D
S
E
E
C
T
S
R
K
P
G
Q
T
V
Chimpanzee
Pan troglodytes
XP_526096
815
91684
S553
S
D
S
E
E
C
T
S
R
K
P
G
Q
T
V
Rhesus Macaque
Macaca mulatta
XP_001118113
806
91202
S544
S
D
S
E
E
C
T
S
R
K
P
G
Q
T
V
Dog
Lupus familis
XP_533350
788
88605
S526
S
D
S
E
E
C
T
S
R
K
S
G
Q
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0I4
808
90941
S546
I
D
S
E
E
C
T
S
R
K
P
G
Q
T
V
Rat
Rattus norvegicus
NP_001102051
808
90800
S546
I
D
S
E
E
C
T
S
R
K
P
G
Q
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509590
778
87501
S516
S
E
S
E
D
C
T
S
R
K
P
G
Q
T
G
Chicken
Gallus gallus
XP_422154
784
88610
L533
Q
C
F
Q
P
R
L
L
N
L
Q
D
S
D
S
Frog
Xenopus laevis
Q66JA8
804
90630
S546
S
D
R
E
E
C
T
S
R
L
G
Q
A
V
N
Zebra Danio
Brachydanio rerio
NP_957369
751
84595
S501
P
V
H
T
N
T
N
S
H
V
S
Q
R
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397232
868
96064
T611
N
N
S
N
D
T
R
T
D
E
L
G
S
S
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192895
443
51775
E193
N
G
H
S
L
I
P
E
V
K
Q
E
K
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
94.1
93.5
N.A.
96.9
96.4
N.A.
86.1
91.5
84.3
60.3
N.A.
N.A.
35.7
N.A.
31.3
Protein Similarity:
100
94.2
95.2
95
N.A.
98.1
98.1
N.A.
89.9
93.6
90.9
72.8
N.A.
N.A.
51.5
N.A.
40.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
80
0
53.3
6.6
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
6.6
53.3
26.6
N.A.
N.A.
53.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
9
0
0
0
67
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
59
0
0
17
0
0
0
9
0
0
9
0
9
9
% D
% Glu:
0
9
0
67
59
0
0
9
0
9
0
9
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
9
67
0
0
9
% G
% His:
0
0
17
0
0
0
0
0
9
0
0
0
0
0
9
% H
% Ile:
17
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
67
0
0
9
0
0
% K
% Leu:
0
0
0
0
9
0
9
9
0
17
9
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
17
9
0
9
9
0
9
0
9
0
0
0
0
0
9
% N
% Pro:
9
0
0
0
9
0
9
0
0
0
50
0
0
0
0
% P
% Gln:
9
0
0
9
0
0
0
0
0
0
17
17
59
0
0
% Q
% Arg:
0
0
9
0
0
9
9
0
67
0
0
0
9
9
0
% R
% Ser:
50
0
67
9
0
0
0
75
0
0
17
0
17
17
9
% S
% Thr:
0
0
0
9
0
17
67
9
0
0
0
0
0
59
0
% T
% Val:
0
9
0
0
0
0
0
0
9
9
0
0
0
9
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _