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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDCD4
All Species:
34.85
Human Site:
S303
Identified Species:
76.67
UniProt:
Q53EL6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53EL6
NP_055271.2
469
51721
S303
D
K
A
T
V
L
L
S
M
S
K
G
G
K
R
Chimpanzee
Pan troglodytes
XP_001143474
469
51730
S303
D
K
A
T
V
L
L
S
M
S
K
G
G
K
R
Rhesus Macaque
Macaca mulatta
XP_001086788
469
51733
S303
D
K
A
T
V
L
L
S
M
S
K
G
G
K
R
Dog
Lupus familis
XP_535012
469
51702
S303
D
K
A
T
V
L
L
S
M
S
K
G
G
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61823
469
51684
S303
D
K
A
T
V
L
L
S
M
S
K
G
G
K
R
Rat
Rattus norvegicus
Q9JID1
469
51718
S303
D
K
A
T
V
L
L
S
M
S
K
G
G
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513214
469
51772
S303
N
R
A
T
V
L
L
S
M
T
K
G
R
K
R
Chicken
Gallus gallus
Q98TX3
467
51689
S301
D
R
A
T
V
L
L
S
V
T
K
G
G
K
R
Frog
Xenopus laevis
NP_001080530
455
50476
R289
D
R
A
A
V
L
L
R
M
T
K
V
G
R
R
Zebra Danio
Brachydanio rerio
NP_945329
470
51893
M304
R
A
A
V
L
L
R
M
S
R
W
T
G
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781080
464
51309
S298
D
R
A
S
N
L
L
S
V
N
H
G
I
H
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98
98.2
N.A.
96.5
96.5
N.A.
93.1
84.8
73.7
69.7
N.A.
N.A.
N.A.
N.A.
47.9
Protein Similarity:
100
100
99.5
99.5
N.A.
98.5
98.7
N.A.
97.8
93.1
86.9
83.8
N.A.
N.A.
N.A.
N.A.
66.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
73.3
80
60
26.6
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
80
33.3
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
100
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
82
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
82
82
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
55
0
0
0
0
0
0
0
0
82
0
0
73
0
% K
% Leu:
0
0
0
0
10
100
91
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
10
73
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
37
0
0
0
0
10
10
0
10
0
0
10
10
100
% R
% Ser:
0
0
0
10
0
0
0
82
10
55
0
0
0
0
0
% S
% Thr:
0
0
0
73
0
0
0
0
0
28
0
10
0
0
0
% T
% Val:
0
0
0
10
82
0
0
0
19
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _