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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDCD4
All Species:
28.79
Human Site:
S68
Identified Species:
63.33
UniProt:
Q53EL6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53EL6
NP_055271.2
469
51721
S68
R
R
L
R
K
N
S
S
R
D
S
G
R
G
D
Chimpanzee
Pan troglodytes
XP_001143474
469
51730
S68
R
R
L
R
K
N
S
S
R
D
S
G
R
G
D
Rhesus Macaque
Macaca mulatta
XP_001086788
469
51733
S68
R
R
L
R
K
N
S
S
R
D
S
G
R
G
D
Dog
Lupus familis
XP_535012
469
51702
S68
R
R
L
R
K
N
S
S
R
D
S
G
R
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q61823
469
51684
S68
R
R
L
R
K
N
S
S
R
D
S
G
R
G
D
Rat
Rattus norvegicus
Q9JID1
469
51718
S68
R
R
L
R
K
N
S
S
R
D
S
G
R
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513214
469
51772
S68
R
R
L
R
K
N
S
S
R
D
S
G
R
G
D
Chicken
Gallus gallus
Q98TX3
467
51689
S66
K
R
R
L
R
K
N
S
S
R
D
S
G
R
G
Frog
Xenopus laevis
NP_001080530
455
50476
K54
K
A
Q
R
R
L
R
K
N
S
S
R
D
S
G
Zebra Danio
Brachydanio rerio
NP_945329
470
51893
N68
V
K
R
R
L
R
K
N
S
S
R
D
S
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781080
464
51309
R57
R
I
T
K
K
A
K
R
R
L
K
R
S
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98
98.2
N.A.
96.5
96.5
N.A.
93.1
84.8
73.7
69.7
N.A.
N.A.
N.A.
N.A.
47.9
Protein Similarity:
100
100
99.5
99.5
N.A.
98.5
98.7
N.A.
97.8
93.1
86.9
83.8
N.A.
N.A.
N.A.
N.A.
66.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
13.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
33.3
26.6
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
64
10
10
10
0
64
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
64
10
73
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
19
10
0
10
73
10
19
10
0
0
10
0
0
0
0
% K
% Leu:
0
0
64
10
10
10
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
64
10
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
73
73
19
82
19
10
10
10
73
10
10
19
64
10
10
% R
% Ser:
0
0
0
0
0
0
64
73
19
19
73
10
19
10
10
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _