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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEZ6
All Species:
18.79
Human Site:
Y981
Identified Species:
68.89
UniProt:
Q53EL9
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53EL9
NP_001092105.1
994
107425
Y981
S
A
F
D
N
P
T
Y
E
T
G
S
L
S
F
Chimpanzee
Pan troglodytes
XP_001139913
994
107509
Y981
S
A
F
D
N
P
T
Y
E
T
G
S
L
S
F
Rhesus Macaque
Macaca mulatta
XP_001110503
978
105882
Y965
S
A
F
D
N
P
T
Y
E
T
G
S
L
S
F
Dog
Lupus familis
XP_548295
981
106521
Y969
S
E
F
D
N
P
T
Y
E
I
G
E
T
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSK2
991
107414
Y978
S
A
F
D
N
P
T
Y
E
T
G
S
L
S
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6AX42
900
98375
Y888
S
D
F
N
N
P
L
Y
E
A
G
D
T
R
E
Zebra Danio
Brachydanio rerio
XP_001919970
988
108347
A973
E
T
G
V
S
M
D
A
M
N
L
R
D
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
91.6
89.3
N.A.
90.5
N.A.
N.A.
N.A.
N.A.
44.8
45.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
93.9
92.3
N.A.
94.2
N.A.
N.A.
N.A.
N.A.
62
62.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
60
N.A.
100
N.A.
N.A.
N.A.
N.A.
46.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
60
N.A.
100
N.A.
N.A.
N.A.
N.A.
53.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
58
0
0
0
0
0
15
0
15
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
72
0
0
15
0
0
0
0
15
15
0
0
% D
% Glu:
15
15
0
0
0
0
0
0
86
0
0
15
0
0
29
% E
% Phe:
0
0
86
0
0
0
0
0
0
0
0
0
0
0
58
% F
% Gly:
0
0
15
0
0
0
0
0
0
0
86
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% K
% Leu:
0
0
0
0
0
0
15
0
0
0
15
0
58
0
0
% L
% Met:
0
0
0
0
0
15
0
0
15
0
0
0
0
0
0
% M
% Asn:
0
0
0
15
86
0
0
0
0
15
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
86
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
15
0
15
0
% R
% Ser:
86
0
0
0
15
0
0
0
0
0
0
58
0
58
0
% S
% Thr:
0
15
0
0
0
0
72
0
0
58
0
0
29
0
0
% T
% Val:
0
0
0
15
0
0
0
0
0
0
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _