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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FNDC3B All Species: 26.97
Human Site: S718 Identified Species: 65.93
UniProt: Q53EP0 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53EP0 NP_001128567.1 1204 132888 S718 T E P E D V A S E V Y H G P E
Chimpanzee Pan troglodytes XP_001165249 1204 132839 S718 T E P E D V A S E V Y H G P E
Rhesus Macaque Macaca mulatta XP_001085354 1204 132875 S718 T E P E D V A S E V Y H G P E
Dog Lupus familis XP_545293 1207 132889 S721 T E P E D V A S E V Y H G P E
Cat Felis silvestris
Mouse Mus musculus Q6NWW9 1207 132746 S721 T E P E N V A S E V Y H G P E
Rat Rattus norvegicus XP_226988 1207 132762 S721 T E P E E V A S E V Y H G P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506146 1207 132652 S721 T E P E A V A S E V Y H G P D
Chicken Gallus gallus Q5ZJP5 1198 131542 R711 Q T E T D E H R E V Y Q G S D
Frog Xenopus laevis NP_001087064 1199 132168 A712 K S E Q E D R A A V Y Q G P E
Zebra Danio Brachydanio rerio NP_001153304 1202 132509 A715 R E G V M E P A E V Y H G S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.9 96.3 N.A. 92.7 92.9 N.A. 85.1 49.6 49.5 69.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 99.1 97.9 N.A. 96.1 96.2 N.A. 92.5 67.7 66.5 82.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 33.3 33.3 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 40 53.3 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 70 20 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 50 10 0 0 0 0 0 0 0 0 30 % D
% Glu: 0 80 20 70 20 20 0 0 90 0 0 0 0 0 70 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 0 100 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 80 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 70 0 0 0 10 0 0 0 0 0 0 80 0 % P
% Gln: 10 0 0 10 0 0 0 0 0 0 0 20 0 0 0 % Q
% Arg: 10 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % R
% Ser: 0 10 0 0 0 0 0 70 0 0 0 0 0 20 0 % S
% Thr: 70 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 10 0 70 0 0 0 100 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _