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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRTC2 All Species: 21.21
Human Site: S255 Identified Species: 58.33
UniProt: Q53ET0 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53ET0 NP_859066.1 693 73302 S255 P G I N I F P S P D Q P A N V
Chimpanzee Pan troglodytes Q5IS70 1186 124883 Y538 S L G S L R P Y P P G P A H L
Rhesus Macaque Macaca mulatta XP_001112030 694 73257 S257 P G I N I F P S P D Q P A N V
Dog Lupus familis XP_855142 696 72986 S256 P G I N I F P S P D Q P P S V
Cat Felis silvestris
Mouse Mus musculus Q3U182 692 73197 S256 P G I N I F P S P D Q P A N V
Rat Rattus norvegicus Q3LRZ1 691 73127 S255 P G I N I F P S P D Q P A N V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233252 620 66878 G203 D K A L S K Q G W D T K K T G
Frog Xenopus laevis Q52KS4 632 69330 Q215 V T K P L P K Q I W E A Q K V
Zebra Danio Brachydanio rerio XP_698544 527 57276 T110 N Q I G N A S T D F Q G T F P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21.8 98.4 89.6 N.A. 92.2 92 N.A. N.A. 38.9 37.2 37.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 31.1 98.5 92.9 N.A. 94.2 94.3 N.A. N.A. 52.3 50.7 47 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 26.6 100 86.6 N.A. 100 100 N.A. N.A. 6.6 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 53.3 100 93.3 N.A. 100 100 N.A. N.A. 6.6 20 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 12 0 0 0 0 0 12 56 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 0 0 0 0 12 67 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % E
% Phe: 0 0 0 0 0 56 0 0 0 12 0 0 0 12 0 % F
% Gly: 0 56 12 12 0 0 0 12 0 0 12 12 0 0 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % H
% Ile: 0 0 67 0 56 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 0 12 12 0 0 12 12 0 0 0 0 12 12 12 0 % K
% Leu: 0 12 0 12 23 0 0 0 0 0 0 0 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 56 12 0 0 0 0 0 0 0 0 45 0 % N
% Pro: 56 0 0 12 0 12 67 0 67 12 0 67 12 0 12 % P
% Gln: 0 12 0 0 0 0 12 12 0 0 67 0 12 0 0 % Q
% Arg: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % R
% Ser: 12 0 0 12 12 0 12 56 0 0 0 0 0 12 0 % S
% Thr: 0 12 0 0 0 0 0 12 0 0 12 0 12 12 0 % T
% Val: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 67 % V
% Trp: 0 0 0 0 0 0 0 0 12 12 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _