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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRTC2
All Species:
12.73
Human Site:
S376
Identified Species:
35
UniProt:
Q53ET0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53ET0
NP_859066.1
693
73302
S376
H
P
S
L
P
A
S
S
L
A
R
H
V
L
P
Chimpanzee
Pan troglodytes
Q5IS70
1186
124883
R670
T
G
T
P
P
G
Y
R
G
T
S
P
P
A
G
Rhesus Macaque
Macaca mulatta
XP_001112030
694
73257
S377
S
H
P
S
L
P
A
S
S
L
A
R
H
A
L
Dog
Lupus familis
XP_855142
696
72986
S379
H
P
S
L
P
A
S
S
L
A
R
H
A
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3U182
692
73197
S377
H
P
S
L
P
A
S
S
L
A
H
H
A
L
P
Rat
Rattus norvegicus
Q3LRZ1
691
73127
S376
H
P
S
L
P
A
S
S
L
A
H
H
A
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233252
620
66878
R323
S
L
S
A
D
S
R
R
P
Q
S
Q
Q
M
S
Frog
Xenopus laevis
Q52KS4
632
69330
G335
V
N
N
H
T
P
P
G
R
N
N
P
T
L
H
Zebra Danio
Brachydanio rerio
XP_698544
527
57276
A230
G
D
V
F
S
F
P
A
V
P
N
E
E
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.8
98.4
89.6
N.A.
92.2
92
N.A.
N.A.
38.9
37.2
37.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
31.1
98.5
92.9
N.A.
94.2
94.3
N.A.
N.A.
52.3
50.7
47
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
93.3
N.A.
86.6
86.6
N.A.
N.A.
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
13.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
20
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
45
12
12
0
45
12
0
34
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
12
12
0
0
% E
% Phe:
0
0
0
12
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
0
0
0
12
0
12
12
0
0
0
0
0
12
% G
% His:
45
12
0
12
0
0
0
0
0
0
23
45
12
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
0
45
12
0
0
0
45
12
0
0
0
56
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
12
12
0
0
0
0
0
0
12
23
0
0
12
0
% N
% Pro:
0
45
12
12
56
23
23
0
12
12
0
23
12
0
45
% P
% Gln:
0
0
0
0
0
0
0
0
0
12
0
12
12
0
0
% Q
% Arg:
0
0
0
0
0
0
12
23
12
0
23
12
0
0
0
% R
% Ser:
23
0
56
12
12
12
45
56
12
0
23
0
0
0
12
% S
% Thr:
12
0
12
0
12
0
0
0
0
12
0
0
12
0
0
% T
% Val:
12
0
12
0
0
0
0
0
12
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _