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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRRC23 All Species: 11.21
Human Site: S127 Identified Species: 22.42
UniProt: Q53EV4 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53EV4 NP_001128689.1 343 39761 S127 A D G N R L R S A Q M N E L P
Chimpanzee Pan troglodytes XP_508974 343 39773 S127 A D G N R L R S A Q M N E L P
Rhesus Macaque Macaca mulatta B6CZ45 192 22142 L16 T S V Q E P P L D Y S F R S I
Dog Lupus familis XP_854389 342 39642 A127 D G N N L R S A Q L N E L P Y
Cat Felis silvestris
Mouse Mus musculus O35125 340 39274 M127 N Q L R S A R M N E L P Y L Q
Rat Rattus norvegicus B6CZ61 192 22144 L16 T S V Q E P P L D Y S F K S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519706 293 32977 G117 N F I Q R V T G L D P L K L G
Chicken Gallus gallus P51890 343 38624 N150 D D L Q L S H N K I T K V N P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120321 376 43263 S159 A D K N E V E S A E L D P M P
Nematode Worm Caenorhab. elegans P45969 326 37341 K139 L V S N K I E K I E N L E A L
Sea Urchin Strong. purpuratus XP_782331 344 39130 S127 C D R N L L A S A K L D E L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36047 338 38869 K129 F N K I K H I K N L E N L T D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 21.8 85.4 N.A. 78.4 22.7 N.A. 59.7 20.7 N.A. N.A. N.A. N.A. 34.8 22.7 54.6
Protein Similarity: 100 99.7 36.1 93 N.A. 89.2 36.4 N.A. 70.5 40.2 N.A. N.A. N.A. N.A. 52.3 41.9 72.9
P-Site Identity: 100 100 0 6.6 N.A. 13.3 0 N.A. 13.3 13.3 N.A. N.A. N.A. N.A. 40 13.3 53.3
P-Site Similarity: 100 100 0 13.3 N.A. 26.6 6.6 N.A. 26.6 20 N.A. N.A. N.A. N.A. 73.3 33.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 0 0 0 9 9 9 34 0 0 0 0 9 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 42 0 0 0 0 0 0 17 9 0 17 0 0 9 % D
% Glu: 0 0 0 0 25 0 17 0 0 25 9 9 34 0 0 % E
% Phe: 9 9 0 0 0 0 0 0 0 0 0 17 0 0 0 % F
% Gly: 0 9 17 0 0 0 0 9 0 0 0 0 0 0 9 % G
% His: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 9 0 9 9 0 9 9 0 0 0 0 9 % I
% Lys: 0 0 17 0 17 0 0 17 9 9 0 9 17 0 0 % K
% Leu: 9 0 17 0 25 25 0 17 9 17 25 17 17 42 9 % L
% Met: 0 0 0 0 0 0 0 9 0 0 17 0 0 9 0 % M
% Asn: 17 9 9 50 0 0 0 9 17 0 17 25 0 9 0 % N
% Pro: 0 0 0 0 0 17 17 0 0 0 9 9 9 9 42 % P
% Gln: 0 9 0 34 0 0 0 0 9 17 0 0 0 0 9 % Q
% Arg: 0 0 9 9 25 9 25 0 0 0 0 0 9 0 0 % R
% Ser: 0 17 9 0 9 9 9 34 0 0 17 0 0 17 0 % S
% Thr: 17 0 0 0 0 0 9 0 0 0 9 0 0 9 0 % T
% Val: 0 9 17 0 0 17 0 0 0 0 0 0 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 17 0 0 9 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _