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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRRC23 All Species: 5.76
Human Site: S180 Identified Species: 11.52
UniProt: Q53EV4 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53EV4 NP_001128689.1 343 39761 S180 L D P E K L I S L H T V E L R
Chimpanzee Pan troglodytes XP_508974 343 39773 S180 L D P E K L I S L H T V E L R
Rhesus Macaque Macaca mulatta B6CZ45 192 22142 Q69 N D L R D F N Q V A S Q L L E
Dog Lupus familis XP_854389 342 39642 L180 D P Q K L L S L H T L E L R G
Cat Felis silvestris
Mouse Mus musculus O35125 340 39274 T180 E R L S S L H T L E L R G N Q
Rat Rattus norvegicus B6CZ61 192 22144 Q69 N D L K D F N Q V V S Q L L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519706 293 32977 C170 L E S L E H L C T L H L R D N
Chicken Gallus gallus P51890 343 38624 K203 L S F N Q L T K L P T G L P H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120321 376 43263 L212 N P Y D L E N L K T L E I G G
Nematode Worm Caenorhab. elegans P45969 326 37341 K192 E G V E T L Q K L S V L S L P
Sea Urchin Strong. purpuratus XP_782331 344 39130 K180 L E P S K L S K L H T L E L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36047 338 38869 N182 D S F E G L S N L E E I W L G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 21.8 85.4 N.A. 78.4 22.7 N.A. 59.7 20.7 N.A. N.A. N.A. N.A. 34.8 22.7 54.6
Protein Similarity: 100 99.7 36.1 93 N.A. 89.2 36.4 N.A. 70.5 40.2 N.A. N.A. N.A. N.A. 52.3 41.9 72.9
P-Site Identity: 100 100 13.3 6.6 N.A. 13.3 13.3 N.A. 6.6 26.6 N.A. N.A. N.A. N.A. 0 26.6 66.6
P-Site Similarity: 100 100 26.6 13.3 N.A. 26.6 40 N.A. 33.3 33.3 N.A. N.A. N.A. N.A. 6.6 33.3 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 17 34 0 9 17 0 0 0 0 0 0 0 0 9 0 % D
% Glu: 17 17 0 34 9 9 0 0 0 17 9 17 25 0 9 % E
% Phe: 0 0 17 0 0 17 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 9 0 0 0 0 0 0 9 9 9 25 % G
% His: 0 0 0 0 0 9 9 0 9 25 9 0 0 0 9 % H
% Ile: 0 0 0 0 0 0 17 0 0 0 0 9 9 0 0 % I
% Lys: 0 0 0 17 25 0 0 25 9 0 0 0 0 0 0 % K
% Leu: 42 0 25 9 17 67 9 17 59 9 25 25 34 59 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 25 0 0 9 0 0 25 9 0 0 0 0 0 9 9 % N
% Pro: 0 17 25 0 0 0 0 0 0 9 0 0 0 9 9 % P
% Gln: 0 0 9 0 9 0 9 17 0 0 0 17 0 0 17 % Q
% Arg: 0 9 0 9 0 0 0 0 0 0 0 9 9 9 25 % R
% Ser: 0 17 9 17 9 0 25 17 0 9 17 0 9 0 0 % S
% Thr: 0 0 0 0 9 0 9 9 9 17 34 0 0 0 0 % T
% Val: 0 0 9 0 0 0 0 0 17 9 9 17 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _