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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC23
All Species:
15.15
Human Site:
S238
Identified Species:
30.3
UniProt:
Q53EV4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53EV4
NP_001128689.1
343
39761
S238
D
N
Q
I
D
T
L
S
G
F
S
R
E
M
K
Chimpanzee
Pan troglodytes
XP_508974
343
39773
S238
D
N
Q
I
D
T
L
S
G
F
S
R
E
M
K
Rhesus Macaque
Macaca mulatta
B6CZ45
192
22142
L126
E
V
N
K
L
A
V
L
P
R
L
R
S
L
T
Dog
Lupus familis
XP_854389
342
39642
S237
D
N
Q
I
E
T
L
S
G
F
S
K
E
M
A
Cat
Felis silvestris
Mouse
Mus musculus
O35125
340
39274
S238
I
E
T
L
N
G
F
S
Q
E
M
K
S
L
Q
Rat
Rattus norvegicus
B6CZ61
192
22144
L126
E
V
N
K
L
A
V
L
P
R
L
R
S
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519706
293
32977
C227
L
I
L
L
E
N
P
C
V
D
E
G
G
Y
R
Chicken
Gallus gallus
P51890
343
38624
P275
F
N
Q
L
K
S
I
P
T
V
S
E
N
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120321
376
43263
S269
S
N
K
I
S
N
L
S
G
F
D
S
R
C
A
Nematode Worm
Caenorhab. elegans
P45969
326
37341
S251
N
N
E
I
K
T
F
S
G
V
E
R
L
E
S
Sea Urchin
Strong. purpuratus
XP_782331
344
39130
D238
D
N
Q
I
S
N
L
D
G
F
S
E
N
M
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36047
338
38869
E241
H
N
F
I
T
K
I
E
G
L
E
K
N
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
21.8
85.4
N.A.
78.4
22.7
N.A.
59.7
20.7
N.A.
N.A.
N.A.
N.A.
34.8
22.7
54.6
Protein Similarity:
100
99.7
36.1
93
N.A.
89.2
36.4
N.A.
70.5
40.2
N.A.
N.A.
N.A.
N.A.
52.3
41.9
72.9
P-Site Identity:
100
100
6.6
80
N.A.
6.6
6.6
N.A.
0
20
N.A.
N.A.
N.A.
N.A.
40
40
60
P-Site Similarity:
100
100
26.6
93.3
N.A.
40
26.6
N.A.
20
53.3
N.A.
N.A.
N.A.
N.A.
46.6
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% C
% Asp:
34
0
0
0
17
0
0
9
0
9
9
0
0
0
0
% D
% Glu:
17
9
9
0
17
0
0
9
0
9
25
17
25
9
9
% E
% Phe:
9
0
9
0
0
0
17
0
0
42
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
59
0
0
9
9
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
9
0
59
0
0
17
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
17
17
9
0
0
0
0
0
25
0
0
25
% K
% Leu:
9
0
9
25
17
0
42
17
0
9
17
0
9
42
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
34
0
% M
% Asn:
9
67
17
0
9
25
0
0
0
0
0
0
25
0
0
% N
% Pro:
0
0
0
0
0
0
9
9
17
0
0
0
0
0
0
% P
% Gln:
0
0
42
0
0
0
0
0
9
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
17
0
42
9
0
17
% R
% Ser:
9
0
0
0
17
9
0
50
0
0
42
9
25
0
9
% S
% Thr:
0
0
9
0
9
34
0
0
9
0
0
0
0
0
17
% T
% Val:
0
17
0
0
0
0
17
0
9
17
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _