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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRRC23 All Species: 8.79
Human Site: T104 Identified Species: 17.58
UniProt: Q53EV4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53EV4 NP_001128689.1 343 39761 T104 D I S E N H L T D L S P L N Y
Chimpanzee Pan troglodytes XP_508974 343 39773 T104 D I S E N H L T D L S P L N Y
Rhesus Macaque Macaca mulatta B6CZ45 192 22142
Dog Lupus familis XP_854389 342 39642 D104 V S E N H L T D L S P L N Y L
Cat Felis silvestris
Mouse Mus musculus O35125 340 39274 S104 E N H I T D I S P L N S L T H
Rat Rattus norvegicus B6CZ61 192 22144
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519706 293 32977 T94 A H N R I S G T E G I T H P R
Chicken Gallus gallus P51890 343 38624 N127 N L K K L H I N Y N N L T E A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120321 376 43263 E136 S G N K L N N E A L R V L S S
Nematode Worm Caenorhab. elegans P45969 326 37341 R116 D L S Y N R I R Q I N G L D K
Sea Urchin Strong. purpuratus XP_782331 344 39130 R104 D L T T N A L R D I S P L S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36047 338 38869 S106 D N K I K H I S S N V N K L T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 21.8 85.4 N.A. 78.4 22.7 N.A. 59.7 20.7 N.A. N.A. N.A. N.A. 34.8 22.7 54.6
Protein Similarity: 100 99.7 36.1 93 N.A. 89.2 36.4 N.A. 70.5 40.2 N.A. N.A. N.A. N.A. 52.3 41.9 72.9
P-Site Identity: 100 100 0 0 N.A. 13.3 0 N.A. 6.6 6.6 N.A. N.A. N.A. N.A. 13.3 26.6 46.6
P-Site Similarity: 100 100 0 6.6 N.A. 46.6 0 N.A. 20 40 N.A. N.A. N.A. N.A. 40 60 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 9 0 0 9 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 42 0 0 0 0 9 0 9 25 0 0 0 0 9 0 % D
% Glu: 9 0 9 17 0 0 0 9 9 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 0 9 0 0 9 0 9 0 0 0 % G
% His: 0 9 9 0 9 34 0 0 0 0 0 0 9 0 9 % H
% Ile: 0 17 0 17 9 0 34 0 0 17 9 0 0 0 0 % I
% Lys: 0 0 17 17 9 0 0 0 0 0 0 0 9 0 9 % K
% Leu: 0 25 0 0 17 9 25 0 9 34 0 17 50 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 17 17 9 34 9 9 9 0 17 25 9 9 17 0 % N
% Pro: 0 0 0 0 0 0 0 0 9 0 9 25 0 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 0 0 0 9 0 9 0 17 0 0 9 0 0 0 9 % R
% Ser: 9 9 25 0 0 9 0 17 9 9 25 9 0 17 17 % S
% Thr: 0 0 9 9 9 0 9 25 0 0 0 9 9 9 9 % T
% Val: 9 0 0 0 0 0 0 0 0 0 9 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 9 0 0 0 0 9 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _