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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC23
All Species:
13.03
Human Site:
T149
Identified Species:
26.06
UniProt:
Q53EV4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53EV4
NP_001128689.1
343
39761
T149
A
Y
N
Q
I
T
D
T
E
G
I
S
H
P
R
Chimpanzee
Pan troglodytes
XP_508974
343
39773
T149
A
Y
N
Q
I
T
D
T
E
G
I
S
H
P
R
Rhesus Macaque
Macaca mulatta
B6CZ45
192
22142
L38
N
E
E
P
R
T
G
L
R
P
L
K
R
S
K
Dog
Lupus familis
XP_854389
342
39642
E149
H
N
Q
I
T
D
T
E
G
I
S
H
P
R
L
Cat
Felis silvestris
Mouse
Mus musculus
O35125
340
39274
I149
Q
I
I
D
T
E
G
I
F
H
P
R
L
G
S
Rat
Rattus norvegicus
B6CZ61
192
22144
L38
S
E
E
P
R
T
G
L
R
P
V
K
Y
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519706
293
32977
T139
R
G
N
Q
L
E
S
T
A
G
L
H
L
P
K
Chicken
Gallus gallus
P51890
343
38624
Q172
N
L
T
V
I
H
L
Q
N
N
Q
L
K
T
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120321
376
43263
T181
N
N
N
K
L
N
S
T
S
G
I
S
H
K
F
Nematode Worm
Caenorhab. elegans
P45969
326
37341
K161
L
G
D
N
R
I
K
K
I
E
N
I
G
H
L
Sea Urchin
Strong. purpuratus
XP_782331
344
39130
T149
A
Y
N
R
I
Q
T
T
E
G
I
N
H
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36047
338
38869
E151
Q
N
S
I
S
K
I
E
N
L
S
T
L
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
21.8
85.4
N.A.
78.4
22.7
N.A.
59.7
20.7
N.A.
N.A.
N.A.
N.A.
34.8
22.7
54.6
Protein Similarity:
100
99.7
36.1
93
N.A.
89.2
36.4
N.A.
70.5
40.2
N.A.
N.A.
N.A.
N.A.
52.3
41.9
72.9
P-Site Identity:
100
100
6.6
0
N.A.
0
6.6
N.A.
33.3
6.6
N.A.
N.A.
N.A.
N.A.
40
0
66.6
P-Site Similarity:
100
100
20
0
N.A.
0
33.3
N.A.
53.3
6.6
N.A.
N.A.
N.A.
N.A.
53.3
6.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
9
17
0
0
0
0
0
0
0
9
% D
% Glu:
0
17
17
0
0
17
0
17
25
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% F
% Gly:
0
17
0
0
0
0
25
0
9
42
0
0
9
9
0
% G
% His:
9
0
0
0
0
9
0
0
0
9
0
17
34
9
0
% H
% Ile:
0
9
9
17
34
9
9
9
9
9
34
9
0
0
0
% I
% Lys:
0
0
0
9
0
9
9
9
0
0
0
17
9
17
25
% K
% Leu:
9
9
0
0
17
0
9
17
0
9
17
9
25
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
25
25
42
9
0
9
0
0
17
9
9
9
0
0
0
% N
% Pro:
0
0
0
17
0
0
0
0
0
17
9
0
9
34
0
% P
% Gln:
17
0
9
25
0
9
0
9
0
0
9
0
0
0
0
% Q
% Arg:
9
0
0
9
25
0
0
0
17
0
0
9
9
9
17
% R
% Ser:
9
0
9
0
9
0
17
0
9
0
17
25
0
17
17
% S
% Thr:
0
0
9
0
17
34
17
42
0
0
0
9
0
9
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
25
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _