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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC23
All Species:
13.03
Human Site:
T226
Identified Species:
26.06
UniProt:
Q53EV4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53EV4
NP_001128689.1
343
39761
T226
E
D
L
S
N
L
T
T
L
H
L
R
D
N
Q
Chimpanzee
Pan troglodytes
XP_508974
343
39773
T226
E
D
L
S
N
L
T
T
L
H
L
R
D
N
Q
Rhesus Macaque
Macaca mulatta
B6CZ45
192
22142
I114
L
Y
L
H
G
N
S
I
Q
H
L
G
E
V
N
Dog
Lupus familis
XP_854389
342
39642
T225
E
N
L
S
N
L
T
T
L
H
L
R
D
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35125
340
39274
L226
S
N
L
T
T
L
H
L
R
D
N
Q
I
E
T
Rat
Rattus norvegicus
B6CZ61
192
22144
I114
L
Y
L
H
G
N
S
I
H
R
L
G
E
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519706
293
32977
P215
L
E
K
L
Q
V
L
P
K
L
R
A
L
I
L
Chicken
Gallus gallus
P51890
343
38624
E263
F
N
I
T
S
L
V
E
L
D
L
S
F
N
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120321
376
43263
I257
E
I
L
V
N
L
K
I
L
H
L
R
S
N
K
Nematode Worm
Caenorhab. elegans
P45969
326
37341
L239
E
P
L
T
N
L
L
L
L
D
V
A
N
N
E
Sea Urchin
Strong. purpuratus
XP_782331
344
39130
T226
E
R
L
E
H
L
T
T
L
H
L
R
D
N
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36047
338
38869
E229
E
E
L
T
N
L
E
E
L
Y
L
S
H
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
21.8
85.4
N.A.
78.4
22.7
N.A.
59.7
20.7
N.A.
N.A.
N.A.
N.A.
34.8
22.7
54.6
Protein Similarity:
100
99.7
36.1
93
N.A.
89.2
36.4
N.A.
70.5
40.2
N.A.
N.A.
N.A.
N.A.
52.3
41.9
72.9
P-Site Identity:
100
100
20
93.3
N.A.
13.3
13.3
N.A.
0
33.3
N.A.
N.A.
N.A.
N.A.
60
40
80
P-Site Similarity:
100
100
33.3
100
N.A.
33.3
26.6
N.A.
13.3
60
N.A.
N.A.
N.A.
N.A.
66.6
66.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
0
0
0
0
0
0
0
25
0
0
34
0
0
% D
% Glu:
59
17
0
9
0
0
9
17
0
0
0
0
17
9
9
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% F
% Gly:
0
0
0
0
17
0
0
0
0
0
0
17
0
0
0
% G
% His:
0
0
0
17
9
0
9
0
9
50
0
0
9
0
0
% H
% Ile:
0
9
9
0
0
0
0
25
0
0
0
0
9
9
0
% I
% Lys:
0
0
9
0
0
0
9
0
9
0
0
0
0
0
9
% K
% Leu:
25
0
84
9
0
75
17
17
67
9
75
0
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
25
0
0
50
17
0
0
0
0
9
0
9
67
17
% N
% Pro:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
9
0
0
9
0
0
42
% Q
% Arg:
0
9
0
0
0
0
0
0
9
9
9
42
0
0
0
% R
% Ser:
9
0
0
25
9
0
17
0
0
0
0
17
9
0
0
% S
% Thr:
0
0
0
34
9
0
34
34
0
0
0
0
0
0
9
% T
% Val:
0
0
0
9
0
9
9
0
0
0
9
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _