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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC23
All Species:
14.85
Human Site:
Y249
Identified Species:
29.7
UniProt:
Q53EV4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53EV4
NP_001128689.1
343
39761
Y249
R
E
M
K
S
L
Q
Y
L
N
L
R
G
N
M
Chimpanzee
Pan troglodytes
XP_508974
343
39773
Y249
R
E
M
K
S
L
Q
Y
L
N
L
R
G
N
M
Rhesus Macaque
Macaca mulatta
B6CZ45
192
22142
N137
R
S
L
T
L
H
G
N
P
M
E
E
E
K
G
Dog
Lupus familis
XP_854389
342
39642
Y248
K
E
M
A
S
L
Q
Y
L
N
L
R
G
N
M
Cat
Felis silvestris
Mouse
Mus musculus
O35125
340
39274
L249
K
S
L
Q
Y
L
N
L
R
S
N
M
I
S
D
Rat
Rattus norvegicus
B6CZ61
192
22144
N137
R
S
L
T
L
H
G
N
P
I
E
E
E
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519706
293
32977
L238
G
G
Y
R
V
E
A
L
V
H
V
P
H
L
E
Chicken
Gallus gallus
P51890
343
38624
L286
E
N
L
E
N
F
Y
L
Q
V
N
K
I
N
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120321
376
43263
Y280
S
R
C
A
K
L
N
Y
L
N
L
R
N
N
E
Nematode Worm
Caenorhab. elegans
P45969
326
37341
F262
R
L
E
S
L
N
D
F
W
A
N
D
N
K
V
Sea Urchin
Strong. purpuratus
XP_782331
344
39130
Y249
E
N
M
R
N
L
Q
Y
I
N
M
R
G
N
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36047
338
38869
L252
K
N
L
K
L
T
T
L
D
V
T
S
N
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
21.8
85.4
N.A.
78.4
22.7
N.A.
59.7
20.7
N.A.
N.A.
N.A.
N.A.
34.8
22.7
54.6
Protein Similarity:
100
99.7
36.1
93
N.A.
89.2
36.4
N.A.
70.5
40.2
N.A.
N.A.
N.A.
N.A.
52.3
41.9
72.9
P-Site Identity:
100
100
6.6
86.6
N.A.
6.6
6.6
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
46.6
6.6
60
P-Site Similarity:
100
100
13.3
93.3
N.A.
40
13.3
N.A.
26.6
33.3
N.A.
N.A.
N.A.
N.A.
46.6
20
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
0
9
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
9
0
0
9
0
0
9
% D
% Glu:
17
25
9
9
0
9
0
0
0
0
17
17
17
0
17
% E
% Phe:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
0
0
17
0
0
0
0
0
34
0
17
% G
% His:
0
0
0
0
0
17
0
0
0
9
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
9
0
0
17
0
9
% I
% Lys:
25
0
0
25
9
0
0
0
0
0
0
9
0
34
9
% K
% Leu:
0
9
42
0
34
50
0
34
34
0
34
0
0
9
0
% L
% Met:
0
0
34
0
0
0
0
0
0
9
9
9
0
0
34
% M
% Asn:
0
25
0
0
17
9
17
17
0
42
25
0
25
50
0
% N
% Pro:
0
0
0
0
0
0
0
0
17
0
0
9
0
0
0
% P
% Gln:
0
0
0
9
0
0
34
0
9
0
0
0
0
0
0
% Q
% Arg:
42
9
0
17
0
0
0
0
9
0
0
42
0
0
0
% R
% Ser:
9
25
0
9
25
0
0
0
0
9
0
9
0
9
0
% S
% Thr:
0
0
0
17
0
9
9
0
0
0
9
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
9
17
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
9
0
9
42
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _