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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53I3
All Species:
15.45
Human Site:
S252
Identified Species:
34
UniProt:
Q53FA7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53FA7
NP_004872.2
332
35536
S252
D
I
N
G
P
L
F
S
K
L
L
F
K
R
G
Chimpanzee
Pan troglodytes
XP_001144287
128
14375
L57
L
L
F
K
R
G
S
L
I
T
S
L
L
R
S
Rhesus Macaque
Macaca mulatta
XP_001099098
332
35523
S252
D
I
N
G
P
L
L
S
K
L
L
H
K
R
G
Dog
Lupus familis
XP_853476
332
35424
S252
D
I
S
G
P
L
F
S
K
L
L
F
K
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80TB8
417
45799
N300
W
W
Q
V
E
K
V
N
P
I
K
L
Y
E
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509453
336
35652
S252
E
V
Q
G
Q
L
L
S
K
L
L
H
K
R
G
Chicken
Gallus gallus
XP_419987
335
35831
A252
E
V
H
G
D
L
L
A
R
L
L
S
K
R
G
Frog
Xenopus laevis
NP_001085954
332
35111
A252
E
I
H
G
D
L
L
A
N
L
L
R
K
R
G
Zebra Danio
Brachydanio rerio
Q8JFV8
484
53544
T357
L
G
Y
L
D
S
E
T
E
L
I
D
Q
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796116
264
28468
Y193
L
R
P
R
S
D
Q
Y
K
A
E
L
V
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38230
334
37000
T259
L
I
P
P
F
S
I
T
R
L
S
P
K
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.5
96
88.8
N.A.
23.5
N.A.
N.A.
72.9
68
66.8
21.8
N.A.
N.A.
N.A.
N.A.
44.5
Protein Similarity:
100
38.5
97.5
94.2
N.A.
39.8
N.A.
N.A.
85.1
81.4
80.1
35.5
N.A.
N.A.
N.A.
N.A.
56
P-Site Identity:
100
6.6
86.6
93.3
N.A.
0
N.A.
N.A.
60
46.6
53.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
86.6
100
N.A.
13.3
N.A.
N.A.
73.3
80
73.3
33.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
19
0
10
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
28
0
0
0
28
10
0
0
0
0
0
10
0
0
0
% D
% Glu:
28
0
0
0
10
0
10
0
10
0
10
0
0
10
10
% E
% Phe:
0
0
10
0
10
0
19
0
0
0
0
19
0
0
0
% F
% Gly:
0
10
0
55
0
10
0
0
0
0
0
0
0
0
55
% G
% His:
0
0
19
0
0
0
0
0
0
0
0
19
0
0
0
% H
% Ile:
0
46
0
0
0
0
10
0
10
10
10
0
0
0
10
% I
% Lys:
0
0
0
10
0
10
0
0
46
0
10
0
64
10
0
% K
% Leu:
37
10
0
10
0
55
37
10
0
73
55
28
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
19
0
0
0
0
10
10
0
0
0
0
10
0
% N
% Pro:
0
0
19
10
28
0
0
0
10
0
0
10
0
0
0
% P
% Gln:
0
0
19
0
10
0
10
0
0
0
0
0
10
0
0
% Q
% Arg:
0
10
0
10
10
0
0
0
19
0
0
10
0
64
0
% R
% Ser:
0
0
10
0
10
19
10
37
0
0
19
10
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
19
0
10
0
0
0
0
0
% T
% Val:
0
19
0
10
0
0
10
0
0
0
0
0
10
0
0
% V
% Trp:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
10
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _