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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53I3
All Species:
16.36
Human Site:
S268
Identified Species:
36
UniProt:
Q53FA7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53FA7
NP_004872.2
332
35536
S268
L
I
T
S
L
L
R
S
R
D
N
K
Y
K
Q
Chimpanzee
Pan troglodytes
XP_001144287
128
14375
L73
D
N
K
Y
K
Q
M
L
V
N
A
F
T
E
Q
Rhesus Macaque
Macaca mulatta
XP_001099098
332
35523
S268
L
I
T
S
L
L
R
S
R
D
N
K
Y
K
Q
Dog
Lupus familis
XP_853476
332
35424
S268
L
I
T
T
L
L
R
S
R
D
K
K
Y
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q80TB8
417
45799
L316
K
V
I
A
G
F
S
L
L
N
L
L
F
K
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509453
336
35652
P268
L
I
T
S
V
L
R
P
R
D
K
K
Y
K
E
Chicken
Gallus gallus
XP_419987
335
35831
S268
I
H
T
S
L
L
R
S
R
D
K
E
Y
K
E
Frog
Xenopus laevis
NP_001085954
332
35111
S268
I
L
G
S
L
L
R
S
R
S
K
K
Y
K
E
Zebra Danio
Brachydanio rerio
Q8JFV8
484
53544
Q373
A
V
M
D
L
Y
R
Q
G
K
V
K
P
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796116
264
28468
F209
T
E
K
A
L
P
H
F
T
P
S
S
P
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38230
334
37000
G275
L
V
R
P
Q
L
Y
G
Y
I
A
D
P
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.5
96
88.8
N.A.
23.5
N.A.
N.A.
72.9
68
66.8
21.8
N.A.
N.A.
N.A.
N.A.
44.5
Protein Similarity:
100
38.5
97.5
94.2
N.A.
39.8
N.A.
N.A.
85.1
81.4
80.1
35.5
N.A.
N.A.
N.A.
N.A.
56
P-Site Identity:
100
6.6
100
86.6
N.A.
13.3
N.A.
N.A.
73.3
66.6
60
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
100
93.3
N.A.
40
N.A.
N.A.
86.6
86.6
80
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
19
0
0
0
0
0
0
19
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
0
0
0
46
0
10
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
10
0
19
46
% E
% Phe:
0
0
0
0
0
10
0
10
0
0
0
10
10
0
0
% F
% Gly:
0
0
10
0
10
0
0
10
10
0
0
0
0
10
0
% G
% His:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
19
37
10
0
0
0
0
0
0
10
0
0
0
0
10
% I
% Lys:
10
0
19
0
10
0
0
0
0
10
37
55
0
64
0
% K
% Leu:
46
10
0
0
64
64
0
19
10
0
10
10
0
0
0
% L
% Met:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
19
19
0
0
0
0
% N
% Pro:
0
0
0
10
0
10
0
10
0
10
0
0
28
0
0
% P
% Gln:
0
0
0
0
10
10
0
10
0
0
0
0
0
0
46
% Q
% Arg:
0
0
10
0
0
0
64
0
55
0
0
0
0
10
0
% R
% Ser:
0
0
0
46
0
0
10
46
0
10
10
10
0
0
0
% S
% Thr:
10
0
46
10
0
0
0
0
10
0
0
0
10
0
0
% T
% Val:
0
28
0
0
10
0
0
0
10
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
10
10
0
10
0
0
0
55
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _