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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53I3
All Species:
8.48
Human Site:
T291
Identified Species:
18.67
UniProt:
Q53FA7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53FA7
NP_004872.2
332
35536
T291
Q
I
L
P
H
F
S
T
E
G
P
Q
R
L
L
Chimpanzee
Pan troglodytes
XP_001144287
128
14375
V96
G
P
Q
R
L
L
P
V
L
D
R
I
Y
P
V
Rhesus Macaque
Macaca mulatta
XP_001099098
332
35523
T291
Q
I
L
P
H
F
S
T
E
G
P
Q
R
L
L
Dog
Lupus familis
XP_853476
332
35424
T291
H
I
L
P
H
F
S
T
E
S
P
Q
R
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80TB8
417
45799
L339
V
V
E
K
L
I
G
L
Y
N
Q
K
K
I
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509453
336
35652
P291
R
I
L
P
H
F
S
P
P
G
E
S
P
R
H
Chicken
Gallus gallus
XP_419987
335
35831
G291
N
V
L
P
Y
F
S
G
G
A
S
P
H
L
Q
Frog
Xenopus laevis
NP_001085954
332
35111
P291
Q
A
L
P
H
F
M
P
G
G
S
V
Q
L
Q
Zebra Danio
Brachydanio rerio
Q8JFV8
484
53544
M396
V
G
D
A
M
R
R
M
Q
E
R
N
N
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796116
264
28468
E232
D
R
V
F
P
L
E
E
I
S
A
A
H
Q
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38230
334
37000
K298
F
G
L
V
N
S
K
K
L
N
I
K
I
Y
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.5
96
88.8
N.A.
23.5
N.A.
N.A.
72.9
68
66.8
21.8
N.A.
N.A.
N.A.
N.A.
44.5
Protein Similarity:
100
38.5
97.5
94.2
N.A.
39.8
N.A.
N.A.
85.1
81.4
80.1
35.5
N.A.
N.A.
N.A.
N.A.
56
P-Site Identity:
100
0
100
86.6
N.A.
0
N.A.
N.A.
46.6
33.3
46.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
6.6
100
86.6
N.A.
26.6
N.A.
N.A.
53.3
46.6
53.3
13.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
0
0
10
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
10
10
28
10
10
0
0
0
0
% E
% Phe:
10
0
0
10
0
55
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
19
0
0
0
0
10
10
19
37
0
0
0
0
10
% G
% His:
10
0
0
0
46
0
0
0
0
0
0
0
19
0
10
% H
% Ile:
0
37
0
0
0
10
0
0
10
0
10
10
10
19
0
% I
% Lys:
0
0
0
10
0
0
10
10
0
0
0
19
10
0
19
% K
% Leu:
0
0
64
0
19
19
0
10
19
0
0
0
0
46
28
% L
% Met:
0
0
0
0
10
0
10
10
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
0
0
0
0
19
0
10
10
0
0
% N
% Pro:
0
10
0
55
10
0
10
19
10
0
28
10
10
10
0
% P
% Gln:
28
0
10
0
0
0
0
0
10
0
10
28
10
10
19
% Q
% Arg:
10
10
0
10
0
10
10
0
0
0
19
0
28
10
0
% R
% Ser:
0
0
0
0
0
10
46
0
0
19
19
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
28
0
0
0
0
0
0
0
% T
% Val:
19
19
10
10
0
0
0
10
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
10
0
0
0
10
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _