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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACSM3 All Species: 13.03
Human Site: Y318 Identified Species: 31.85
UniProt: Q53FZ2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53FZ2 NP_005613.2 586 66153 Y318 I L Q T L S K Y P I T V F C S
Chimpanzee Pan troglodytes XP_001158501 586 66136 Y318 I L Q T L S K Y P I T V F C S
Rhesus Macaque Macaca mulatta XP_001089634 586 65967 Y318 V L Q T L S K Y P I T V F C S
Dog Lupus familis XP_851120 580 65432 F312 I F Q T L S K F P I T V F C S
Cat Felis silvestris
Mouse Mus musculus Q3UNX5 580 65605 F312 I L Q T L S K F P I T V F C S
Rat Rattus norvegicus Q6SKG1 580 65695 F312 I L Q T L S K F P I T V F C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508475 585 66369 F318 I L D T L S R F P I S V F C S
Chicken Gallus gallus XP_424601 578 64821 P311 F E S L S R Y P I T V F C S A
Frog Xenopus laevis NP_001086370 584 65403 F313 V L Q T L S T F P I T T F C S
Zebra Danio Brachydanio rerio NP_001104706 591 66900 Y321 V L K T L S H Y P I T T F C T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 95 87.1 N.A. 85.6 83.9 N.A. 74.2 64.3 65.8 63.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 97 94.5 N.A. 92.6 92.1 N.A. 87 79 79.3 78.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 93.3 93.3 N.A. 73.3 0 73.3 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 93.3 6.6 86.6 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 90 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 10 0 0 0 0 0 50 0 0 0 10 90 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 60 0 0 0 0 0 0 0 10 90 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 60 0 0 0 0 0 0 0 0 % K
% Leu: 0 80 0 10 90 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 90 0 0 0 0 0 0 % P
% Gln: 0 0 70 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 0 10 90 0 0 0 0 10 0 0 10 80 % S
% Thr: 0 0 0 90 0 0 10 0 0 10 80 20 0 0 10 % T
% Val: 30 0 0 0 0 0 0 0 0 0 10 70 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 40 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _