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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSM3
All Species:
38.79
Human Site:
Y457
Identified Species:
94.81
UniProt:
Q53FZ2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53FZ2
NP_005613.2
586
66153
Y457
S
T
L
R
G
N
F
Y
I
T
G
D
R
G
Y
Chimpanzee
Pan troglodytes
XP_001158501
586
66136
Y457
S
T
L
R
G
N
F
Y
I
T
G
D
R
G
Y
Rhesus Macaque
Macaca mulatta
XP_001089634
586
65967
Y457
S
T
L
R
G
N
F
Y
I
T
G
D
R
G
Y
Dog
Lupus familis
XP_851120
580
65432
Y451
S
T
L
R
G
N
F
Y
I
T
G
D
R
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q3UNX5
580
65605
Y451
S
T
L
R
G
S
F
Y
I
T
G
D
R
G
Y
Rat
Rattus norvegicus
Q6SKG1
580
65695
Y451
S
T
L
R
G
N
F
Y
I
T
G
D
R
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508475
585
66369
Y456
S
T
L
R
G
D
F
Y
I
T
G
D
R
G
Y
Chicken
Gallus gallus
XP_424601
578
64821
Y449
A
T
V
R
G
D
F
Y
V
T
G
D
R
G
L
Frog
Xenopus laevis
NP_001086370
584
65403
Y452
S
T
R
R
G
N
F
Y
L
T
G
D
R
G
I
Zebra Danio
Brachydanio rerio
NP_001104706
591
66900
Y460
E
C
F
R
G
D
F
Y
L
T
G
D
R
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95
87.1
N.A.
85.6
83.9
N.A.
74.2
64.3
65.8
63.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
97
94.5
N.A.
92.6
92.1
N.A.
87
79
79.3
78.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
93.3
66.6
80
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
86.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
30
0
0
0
0
0
100
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
100
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
100
0
0
0
0
0
100
0
0
100
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
70
0
0
0
0
0
20
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
100
0
0
0
0
0
0
0
0
100
0
0
% R
% Ser:
80
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
90
0
0
0
0
0
0
0
100
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
70
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _