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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IFI44L All Species: 3.64
Human Site: S377 Identified Species: 16
UniProt: Q53G44 Number Species: 5
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53G44 NP_006811.2 452 51322 S377 N F L N M S R S M T S Q S R V
Chimpanzee Pan troglodytes P27473 444 50452 C365 D L I E I E R C V P V R S K L
Rhesus Macaque Macaca mulatta XP_001100154 371 42382 F306 I T P E H S T F I T S P S L K
Dog Lupus familis XP_537104 565 65271 A468 N F L N M A K A M T S Q S Q I
Cat Felis silvestris
Mouse Mus musculus Q9BDB7 447 49661 T377 S F A N M T E T V T S L S Q V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_683129 488 54745 K422 H V E K D L Y K I Y L S S Y I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.3 71.6 41.5 N.A. 55.3 N.A. N.A. N.A. N.A. N.A. 32.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 63.5 76.7 56.8 N.A. 74.1 N.A. N.A. N.A. N.A. N.A. 51.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 26.6 66.6 N.A. 46.6 N.A. N.A. N.A. N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 60 33.3 100 N.A. 80 N.A. N.A. N.A. N.A. N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 0 17 0 17 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % C
% Asp: 17 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 17 34 0 17 17 0 0 0 0 0 0 0 0 % E
% Phe: 0 50 0 0 0 0 0 17 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 17 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 17 0 17 0 17 0 0 0 34 0 0 0 0 0 34 % I
% Lys: 0 0 0 17 0 0 17 17 0 0 0 0 0 17 17 % K
% Leu: 0 17 34 0 0 17 0 0 0 0 17 17 0 17 17 % L
% Met: 0 0 0 0 50 0 0 0 34 0 0 0 0 0 0 % M
% Asn: 34 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 17 0 0 0 0 0 0 17 0 17 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 34 0 34 0 % Q
% Arg: 0 0 0 0 0 0 34 0 0 0 0 17 0 17 0 % R
% Ser: 17 0 0 0 0 34 0 17 0 0 67 17 100 0 0 % S
% Thr: 0 17 0 0 0 17 17 17 0 67 0 0 0 0 0 % T
% Val: 0 17 0 0 0 0 0 0 34 0 17 0 0 0 34 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 17 0 0 17 0 0 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _