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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHLDA2
All Species:
13.94
Human Site:
Y69
Identified Species:
38.33
UniProt:
Q53GA4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53GA4
NP_003302.1
152
17092
Y69
E
R
T
G
K
Y
V
Y
F
T
I
V
T
T
D
Chimpanzee
Pan troglodytes
XP_001155149
155
17329
Y69
E
R
T
G
K
Y
V
Y
F
T
I
V
T
T
D
Rhesus Macaque
Macaca mulatta
XP_001094620
152
16905
Y69
E
R
T
G
K
Y
V
Y
F
T
I
V
T
T
D
Dog
Lupus familis
XP_854063
224
24864
Y104
E
R
K
G
K
Y
M
Y
F
T
V
V
M
A
E
Cat
Felis silvestris
Mouse
Mus musculus
O08969
144
16709
H73
L
K
V
D
C
V
E
H
T
S
K
Y
V
Y
F
Rat
Rattus norvegicus
Q5PQT7
125
13716
R55
P
K
E
L
S
F
S
R
I
K
A
V
E
C
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507504
126
14311
Q56
R
P
K
E
L
S
F
Q
S
I
L
K
L
D
C
Chicken
Gallus gallus
Frog
Xenopus laevis
A1L2W9
125
14308
S55
C
K
E
L
K
F
Q
S
I
K
K
V
D
C
V
Zebra Danio
Brachydanio rerio
Q503L1
136
15690
H66
K
K
V
D
C
V
E
H
T
G
K
F
V
Y
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
92.7
33
N.A.
62.5
40.7
N.A.
57.8
N.A.
51.9
48.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98
93.4
43.7
N.A.
68.4
51.9
N.A.
64.4
N.A.
63.1
66.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
60
N.A.
0
6.6
N.A.
0
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
20
20
N.A.
6.6
N.A.
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
12
0
0
12
0
% A
% Cys:
12
0
0
0
23
0
0
0
0
0
0
0
0
23
12
% C
% Asp:
0
0
0
23
0
0
0
0
0
0
0
0
12
12
34
% D
% Glu:
45
0
23
12
0
0
23
0
0
0
0
0
12
0
12
% E
% Phe:
0
0
0
0
0
23
12
0
45
0
0
12
0
0
23
% F
% Gly:
0
0
0
45
0
0
0
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
23
12
34
0
0
0
0
% I
% Lys:
12
45
23
0
56
0
0
0
0
23
34
12
0
0
0
% K
% Leu:
12
0
0
23
12
0
0
0
0
0
12
0
12
0
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
12
12
0
0
0
0
0
0
0
% Q
% Arg:
12
45
0
0
0
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
12
12
12
12
12
12
0
0
0
0
0
% S
% Thr:
0
0
34
0
0
0
0
0
23
45
0
0
34
34
0
% T
% Val:
0
0
23
0
0
23
34
0
0
0
12
67
23
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
45
0
45
0
0
0
12
0
23
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _