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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHO1
All Species:
25.15
Human Site:
S402
Identified Species:
79.05
UniProt:
Q53GL0
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53GL0
NP_057358.2
409
46237
S402
L
R
Q
T
T
P
H
S
Q
Y
R
K
S
L
M
Chimpanzee
Pan troglodytes
XP_513771
409
46277
S402
L
R
Q
T
T
P
H
S
Q
Y
R
K
S
L
M
Rhesus Macaque
Macaca mulatta
XP_001098879
408
46057
S401
L
R
Q
T
T
P
H
S
Q
Y
R
K
S
L
M
Dog
Lupus familis
XP_849847
408
46152
S401
L
R
P
A
A
Q
H
S
Q
Y
R
K
S
L
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIY0
408
45978
S401
L
R
Q
T
S
Q
H
S
Q
Y
R
K
S
L
M
Rat
Rattus norvegicus
Q5BJM5
408
46049
S401
L
R
Q
T
S
Q
H
S
Q
Y
R
K
S
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3C8
423
48133
S416
D
C
N
P
K
Q
S
S
Q
Y
R
K
S
M
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4IG55
520
58733
S512
L
S
K
T
G
M
A
S
Q
K
L
Q
Q
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.5
89.7
N.A.
89.9
89.2
N.A.
N.A.
74.4
N.A.
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99
92.6
N.A.
92.1
91.9
N.A.
N.A.
82.5
N.A.
54
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
86.6
86.6
N.A.
N.A.
46.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
93.3
93.3
N.A.
N.A.
53.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
13
0
13
0
0
0
0
0
0
0
0
% A
% Cys:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
75
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
13
0
0
0
0
13
0
88
0
13
0
% K
% Leu:
88
0
0
0
0
0
0
0
0
0
13
0
0
75
0
% L
% Met:
0
0
0
0
0
13
0
0
0
0
0
0
0
13
88
% M
% Asn:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
13
13
0
38
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
63
0
0
50
0
0
100
0
0
13
13
0
0
% Q
% Arg:
0
75
0
0
0
0
0
0
0
0
88
0
0
0
0
% R
% Ser:
0
13
0
0
25
0
13
100
0
0
0
0
88
0
13
% S
% Thr:
0
0
0
75
38
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
88
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _