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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLE1
All Species:
22.12
Human Site:
S123
Identified Species:
48.67
UniProt:
Q53GS7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53GS7
NP_001003722.1
698
79836
S123
E
S
M
V
L
Q
S
S
R
G
I
K
V
E
G
Chimpanzee
Pan troglodytes
XP_001159347
697
79620
S123
E
S
M
V
L
P
S
S
R
G
I
K
V
E
G
Rhesus Macaque
Macaca mulatta
XP_001110844
698
79589
S123
E
S
M
V
L
Q
S
S
R
G
I
K
V
E
G
Dog
Lupus familis
XP_537825
623
70823
S123
E
P
M
V
L
Q
S
S
R
G
I
K
V
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R322
699
79556
S125
E
P
I
A
P
Q
S
S
R
A
I
K
V
E
G
Rat
Rattus norvegicus
Q4KLN4
698
79473
S124
E
P
I
A
L
Q
S
S
R
A
I
K
V
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415496
726
82611
S152
V
L
P
I
P
P
V
S
K
M
A
K
V
E
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRB1
695
79110
A128
E
V
V
V
E
A
P
A
V
S
P
E
A
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4W1
677
77341
L140
D
Q
L
Q
Q
K
A
L
R
E
R
N
E
S
L
Honey Bee
Apis mellifera
XP_396401
527
60485
K77
E
Q
L
S
E
N
F
K
D
K
N
S
F
T
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202839
632
72578
V127
E
K
I
V
K
E
R
V
K
E
R
Q
W
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.1
71.6
N.A.
83.4
84.2
N.A.
N.A.
57.5
N.A.
50
N.A.
23.7
25.7
N.A.
33.6
Protein Similarity:
100
99.4
98.2
78
N.A.
90.1
90.2
N.A.
N.A.
73.9
N.A.
69.3
N.A.
44.5
44.5
N.A.
51.1
P-Site Identity:
100
93.3
100
93.3
N.A.
66.6
73.3
N.A.
N.A.
33.3
N.A.
13.3
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
93.3
100
93.3
N.A.
73.3
80
N.A.
N.A.
46.6
N.A.
33.3
N.A.
33.3
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
10
10
10
0
19
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
82
0
0
0
19
10
0
0
0
19
0
10
10
64
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
37
0
0
0
0
64
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
28
10
0
0
0
0
0
0
55
0
0
0
0
% I
% Lys:
0
10
0
0
10
10
0
10
19
10
0
64
0
0
0
% K
% Leu:
0
10
19
0
46
0
0
10
0
0
0
0
0
0
28
% L
% Met:
0
0
37
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
10
10
0
0
0
% N
% Pro:
0
28
10
0
19
19
10
0
0
0
10
0
0
0
0
% P
% Gln:
0
19
0
10
10
46
0
0
0
0
0
10
0
10
0
% Q
% Arg:
0
0
0
0
0
0
10
0
64
0
19
0
0
0
0
% R
% Ser:
0
28
0
10
0
0
55
64
0
10
0
10
0
19
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
10
10
10
55
0
0
10
10
10
0
0
0
64
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _