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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLE1
All Species:
21.21
Human Site:
S297
Identified Species:
46.67
UniProt:
Q53GS7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53GS7
NP_001003722.1
698
79836
S297
I
S
G
I
I
R
A
S
S
E
S
S
Y
P
T
Chimpanzee
Pan troglodytes
XP_001159347
697
79620
S297
I
S
G
I
I
R
A
S
S
E
S
S
Y
P
T
Rhesus Macaque
Macaca mulatta
XP_001110844
698
79589
S297
I
S
G
I
I
R
A
S
S
E
S
G
C
P
T
Dog
Lupus familis
XP_537825
623
70823
E266
N
Q
Q
L
D
T
S
E
Q
H
R
D
T
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R322
699
79556
T299
I
S
S
I
I
R
T
T
L
E
S
G
Y
P
T
Rat
Rattus norvegicus
Q4KLN4
698
79473
T298
I
S
G
I
I
R
T
T
L
E
S
G
Y
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415496
726
82611
T326
V
S
G
L
I
R
T
T
S
E
R
G
F
P
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRB1
695
79110
A318
L
S
E
V
V
P
A
A
A
D
D
Q
F
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4W1
677
77341
A273
L
D
I
I
K
Q
L
A
E
F
S
E
Q
I
Q
Honey Bee
Apis mellifera
XP_396401
527
60485
T195
S
S
D
I
S
Q
I
T
S
S
T
A
N
I
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202839
632
72578
C249
I
V
H
L
L
Q
S
C
S
H
K
E
H
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.1
71.6
N.A.
83.4
84.2
N.A.
N.A.
57.5
N.A.
50
N.A.
23.7
25.7
N.A.
33.6
Protein Similarity:
100
99.4
98.2
78
N.A.
90.1
90.2
N.A.
N.A.
73.9
N.A.
69.3
N.A.
44.5
44.5
N.A.
51.1
P-Site Identity:
100
100
86.6
0
N.A.
66.6
73.3
N.A.
N.A.
46.6
N.A.
20
N.A.
13.3
20
N.A.
13.3
P-Site Similarity:
100
100
86.6
13.3
N.A.
73.3
80
N.A.
N.A.
80
N.A.
73.3
N.A.
33.3
46.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
37
19
10
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% C
% Asp:
0
10
10
0
10
0
0
0
0
10
10
10
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
10
10
55
0
19
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
19
0
0
% F
% Gly:
0
0
46
0
0
0
0
0
0
0
0
37
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
19
0
0
10
0
0
% H
% Ile:
55
0
10
64
55
0
10
0
0
0
0
0
0
19
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
10
% K
% Leu:
19
0
0
28
10
0
10
0
19
0
0
0
0
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
64
0
% P
% Gln:
0
10
10
0
0
28
0
0
10
0
0
10
10
0
10
% Q
% Arg:
0
0
0
0
0
55
0
0
0
0
19
0
0
0
0
% R
% Ser:
10
73
10
0
10
0
19
28
55
10
55
19
0
0
28
% S
% Thr:
0
0
0
0
0
10
28
37
0
0
10
0
10
0
46
% T
% Val:
10
10
0
10
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
37
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _