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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLE1
All Species:
27.88
Human Site:
S453
Identified Species:
61.33
UniProt:
Q53GS7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53GS7
NP_001003722.1
698
79836
S453
D
K
I
H
S
L
L
S
G
K
P
V
Q
S
G
Chimpanzee
Pan troglodytes
XP_001159347
697
79620
S452
D
K
I
H
S
L
L
S
G
K
P
V
Q
S
G
Rhesus Macaque
Macaca mulatta
XP_001110844
698
79589
S453
D
K
I
H
S
L
L
S
G
K
P
V
Q
S
G
Dog
Lupus familis
XP_537825
623
70823
W389
V
Q
D
S
T
M
Q
W
Y
Q
Q
L
Q
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R322
699
79556
S454
D
K
I
H
S
L
L
S
G
K
P
V
Q
S
G
Rat
Rattus norvegicus
Q4KLN4
698
79473
S453
D
K
I
H
S
L
L
S
G
K
P
V
Q
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415496
726
82611
S481
D
K
L
N
N
L
L
S
G
K
P
V
Q
S
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRB1
695
79110
S473
E
K
I
D
K
L
L
S
R
R
P
V
T
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4W1
677
77341
A437
D
K
L
Y
S
F
F
A
G
Q
P
T
K
V
M
Honey Bee
Apis mellifera
XP_396401
527
60485
G317
A
K
K
I
V
N
Q
G
E
T
L
V
S
S
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202839
632
72578
S390
H
R
I
K
D
L
L
S
G
L
E
V
Q
M
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.1
71.6
N.A.
83.4
84.2
N.A.
N.A.
57.5
N.A.
50
N.A.
23.7
25.7
N.A.
33.6
Protein Similarity:
100
99.4
98.2
78
N.A.
90.1
90.2
N.A.
N.A.
73.9
N.A.
69.3
N.A.
44.5
44.5
N.A.
51.1
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
73.3
N.A.
53.3
N.A.
33.3
20
N.A.
46.6
P-Site Similarity:
100
100
100
40
N.A.
100
100
N.A.
N.A.
93.3
N.A.
66.6
N.A.
66.6
20
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
64
0
10
10
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
10
0
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
73
0
0
0
0
0
46
% G
% His:
10
0
0
46
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
64
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
82
10
10
10
0
0
0
0
55
0
0
10
0
10
% K
% Leu:
0
0
19
0
0
73
73
0
0
10
10
10
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
10
% M
% Asn:
0
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
73
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
19
0
0
19
10
0
73
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
10
10
0
0
0
0
0
% R
% Ser:
0
0
0
10
55
0
0
73
0
0
0
0
10
73
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
10
0
10
10
0
10
% T
% Val:
10
0
0
0
10
0
0
0
0
0
0
82
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _