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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLE1
All Species:
25.76
Human Site:
S459
Identified Species:
56.67
UniProt:
Q53GS7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53GS7
NP_001003722.1
698
79836
S459
L
S
G
K
P
V
Q
S
G
G
R
S
V
S
V
Chimpanzee
Pan troglodytes
XP_001159347
697
79620
S458
L
S
G
K
P
V
Q
S
G
G
R
S
V
S
V
Rhesus Macaque
Macaca mulatta
XP_001110844
698
79589
S459
L
S
G
K
P
V
Q
S
G
G
R
S
V
S
V
Dog
Lupus familis
XP_537825
623
70823
E395
Q
W
Y
Q
Q
L
Q
E
A
S
N
Q
C
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R322
699
79556
S460
L
S
G
K
P
V
Q
S
G
G
R
S
V
S
V
Rat
Rattus norvegicus
Q4KLN4
698
79473
S459
L
S
G
K
P
V
Q
S
G
G
R
S
V
C
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415496
726
82611
S487
L
S
G
K
P
V
Q
S
V
G
E
T
V
L
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRB1
695
79110
S479
L
S
R
R
P
V
T
S
A
G
K
T
V
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4W1
677
77341
V443
F
A
G
Q
P
T
K
V
M
N
G
T
I
T
I
Honey Bee
Apis mellifera
XP_396401
527
60485
S323
Q
G
E
T
L
V
S
S
K
P
K
M
A
F
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202839
632
72578
M396
L
S
G
L
E
V
Q
M
T
N
R
R
V
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.1
71.6
N.A.
83.4
84.2
N.A.
N.A.
57.5
N.A.
50
N.A.
23.7
25.7
N.A.
33.6
Protein Similarity:
100
99.4
98.2
78
N.A.
90.1
90.2
N.A.
N.A.
73.9
N.A.
69.3
N.A.
44.5
44.5
N.A.
51.1
P-Site Identity:
100
100
100
6.6
N.A.
100
93.3
N.A.
N.A.
73.3
N.A.
53.3
N.A.
13.3
13.3
N.A.
46.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
93.3
N.A.
N.A.
80
N.A.
73.3
N.A.
60
20
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
19
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
10
0
0
10
0
0
10
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
10
73
0
0
0
0
0
46
64
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% I
% Lys:
0
0
0
55
0
0
10
0
10
0
19
0
0
10
0
% K
% Leu:
73
0
0
10
10
10
0
0
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
10
10
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
19
10
0
0
0
0
% N
% Pro:
0
0
0
0
73
0
0
0
0
10
0
0
0
0
10
% P
% Gln:
19
0
0
19
10
0
73
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
10
10
0
0
0
0
0
0
55
10
0
0
0
% R
% Ser:
0
73
0
0
0
0
10
73
0
10
0
46
0
46
0
% S
% Thr:
0
0
0
10
0
10
10
0
10
0
0
28
0
10
10
% T
% Val:
0
0
0
0
0
82
0
10
10
0
0
0
73
10
55
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _