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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLE1
All Species:
17.27
Human Site:
T115
Identified Species:
38
UniProt:
Q53GS7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53GS7
NP_001003722.1
698
79836
T115
G
K
D
E
S
Q
H
T
E
S
M
V
L
Q
S
Chimpanzee
Pan troglodytes
XP_001159347
697
79620
T115
G
K
D
E
S
Q
H
T
E
S
M
V
L
P
S
Rhesus Macaque
Macaca mulatta
XP_001110844
698
79589
T115
G
K
D
E
S
Q
H
T
E
S
M
V
L
Q
S
Dog
Lupus familis
XP_537825
623
70823
T115
G
K
H
K
S
Q
Y
T
E
P
M
V
L
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R322
699
79556
T117
S
T
H
E
S
P
F
T
E
P
I
A
P
Q
S
Rat
Rattus norvegicus
Q4KLN4
698
79473
T116
S
A
H
E
S
P
F
T
E
P
I
A
L
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415496
726
82611
E144
G
V
L
E
V
N
Q
E
V
L
P
I
P
P
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRB1
695
79110
A120
E
K
E
E
E
E
K
A
E
V
V
V
E
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4W1
677
77341
R132
Q
R
K
E
E
R
Q
R
D
Q
L
Q
Q
K
A
Honey Bee
Apis mellifera
XP_396401
527
60485
R69
V
S
R
S
H
M
A
R
E
Q
L
S
E
N
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202839
632
72578
W119
I
F
Q
C
E
Q
E
W
E
K
I
V
K
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.1
71.6
N.A.
83.4
84.2
N.A.
N.A.
57.5
N.A.
50
N.A.
23.7
25.7
N.A.
33.6
Protein Similarity:
100
99.4
98.2
78
N.A.
90.1
90.2
N.A.
N.A.
73.9
N.A.
69.3
N.A.
44.5
44.5
N.A.
51.1
P-Site Identity:
100
93.3
100
73.3
N.A.
40
46.6
N.A.
N.A.
13.3
N.A.
26.6
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
93.3
100
86.6
N.A.
46.6
53.3
N.A.
N.A.
20
N.A.
46.6
N.A.
46.6
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
10
10
0
0
0
19
0
10
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
28
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
10
0
10
73
28
10
10
10
82
0
0
0
19
10
0
% E
% Phe:
0
10
0
0
0
0
19
0
0
0
0
0
0
0
10
% F
% Gly:
46
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
28
0
10
0
28
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
28
10
0
0
0
% I
% Lys:
0
46
10
10
0
0
10
0
0
10
0
0
10
10
0
% K
% Leu:
0
0
10
0
0
0
0
0
0
10
19
0
46
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
37
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
19
0
0
0
28
10
0
19
19
10
% P
% Gln:
10
0
10
0
0
46
19
0
0
19
0
10
10
46
0
% Q
% Arg:
0
10
10
0
0
10
0
19
0
0
0
0
0
0
10
% R
% Ser:
19
10
0
10
55
0
0
0
0
28
0
10
0
0
55
% S
% Thr:
0
10
0
0
0
0
0
55
0
0
0
0
0
0
0
% T
% Val:
10
10
0
0
10
0
0
0
10
10
10
55
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _