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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP39 All Species: 27.88
Human Site: S295 Identified Species: 47.18
UniProt: Q53GS9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53GS9 NP_006581.2 565 65381 S295 R N F K A H V S P H E M L Q A
Chimpanzee Pan troglodytes XP_515591 565 65314 S295 R N F K A H V S P H E M L Q A
Rhesus Macaque Macaca mulatta XP_001089375 565 65373 S295 R N F K A H V S P H E M L Q A
Dog Lupus familis XP_532977 561 64749 S291 R N F K A H V S P H E M L Q A
Cat Felis silvestris
Mouse Mus musculus Q3TIX9 564 65128 S294 R N F K A H V S P H E M L Q A
Rat Rattus norvegicus NP_001100067 568 65325 S294 R N F K A H V S P H E M L Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518784 529 60631 Q276 L C S K K T F Q I T K Q G D G
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001073539 497 57657 T245 S K K T F Q I T K Q G D A V D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573334 494 57485 S242 Q A V V L W S S K R F Q I T E
Honey Bee Apis mellifera XP_394503 491 57190 A239 S P H E M L Q A V V L W S K K
Nematode Worm Caenorhab. elegans NP_494298 602 70982 S326 R A L R T H V S P H E M L Q A
Sea Urchin Strong. purpuratus XP_001178710 517 59237 W265 D P V D V L S W F I N A L H S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C585 871 98152 V346 W A P G A S T V A P R T F K A
Baker's Yeast Sacchar. cerevisiae P43589 448 52148 C196 F I K R L S I C V K K I W S P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.4 98 N.A. 97.3 94.1 N.A. 86 N.A. N.A. 77.3 N.A. 55.5 59.1 53.9 61.5
Protein Similarity: 100 99.8 99.4 98 N.A. 98.2 95.5 N.A. 88.5 N.A. N.A. 81 N.A. 69 70.6 69.9 73.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 N.A. N.A. 0 N.A. 6.6 0 73.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 N.A. N.A. 13.3 N.A. 20 20 80 13.3
Percent
Protein Identity: N.A. N.A. N.A. 20.5 27 N.A.
Protein Similarity: N.A. N.A. N.A. 36.1 45.8 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 0 0 50 0 0 8 8 0 0 8 8 0 58 % A
% Cys: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 8 0 0 0 0 0 0 0 8 0 8 8 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 50 0 0 0 8 % E
% Phe: 8 0 43 0 8 0 8 0 8 0 8 0 8 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 0 0 8 0 8 0 8 % G
% His: 0 0 8 0 0 50 0 0 0 50 0 0 0 8 0 % H
% Ile: 0 8 0 0 0 0 15 0 8 8 0 8 8 0 0 % I
% Lys: 0 8 15 50 8 0 0 0 15 8 15 0 0 15 8 % K
% Leu: 8 0 8 0 15 15 0 0 0 0 8 0 58 0 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 50 0 0 0 % M
% Asn: 0 43 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 15 8 0 0 0 0 0 50 8 0 0 0 0 8 % P
% Gln: 8 0 0 0 0 8 8 8 0 8 0 15 0 50 0 % Q
% Arg: 50 0 0 15 0 0 0 0 0 8 8 0 0 0 0 % R
% Ser: 15 0 8 0 0 15 15 58 0 0 0 0 8 8 8 % S
% Thr: 0 0 0 8 8 8 8 8 0 8 0 8 0 8 0 % T
% Val: 0 0 15 8 8 0 50 8 15 8 0 0 0 8 0 % V
% Trp: 8 0 0 0 0 8 0 8 0 0 0 8 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _