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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP39
All Species:
18.18
Human Site:
S43
Identified Species:
30.77
UniProt:
Q53GS9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53GS9
NP_006581.2
565
65381
S43
R
E
P
E
A
A
S
S
R
G
S
P
V
R
V
Chimpanzee
Pan troglodytes
XP_515591
565
65314
S43
R
E
P
E
A
A
S
S
R
G
S
P
V
R
V
Rhesus Macaque
Macaca mulatta
XP_001089375
565
65373
S43
R
E
P
E
A
A
S
S
R
G
S
P
V
R
V
Dog
Lupus familis
XP_532977
561
64749
G41
A
E
A
P
S
S
R
G
S
P
V
R
V
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3TIX9
564
65128
S43
K
E
P
E
A
A
S
S
R
G
S
P
V
R
V
Rat
Rattus norvegicus
NP_001100067
568
65325
S43
K
E
P
E
A
A
S
S
R
G
S
P
V
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518784
529
60631
G45
R
L
H
G
S
R
G
G
G
V
C
A
C
A
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073539
497
57657
E16
R
D
F
D
E
D
E
E
E
E
V
R
V
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573334
494
57485
K13
A
P
A
A
K
R
M
K
L
E
K
T
P
A
N
Honey Bee
Apis mellifera
XP_394503
491
57190
Q10
T
N
Q
S
G
F
Q
Q
K
R
K
L
M
I
E
Nematode Worm
Caenorhab. elegans
NP_494298
602
70982
E74
E
E
K
Q
E
Q
E
E
E
D
G
E
I
R
D
Sea Urchin
Strong. purpuratus
XP_001178710
517
59237
G36
V
P
S
K
T
P
K
G
T
K
E
D
K
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C585
871
98152
P42
K
D
A
Q
D
S
M
P
S
E
S
V
E
K
R
Baker's Yeast
Sacchar. cerevisiae
P43589
448
52148
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
98
N.A.
97.3
94.1
N.A.
86
N.A.
N.A.
77.3
N.A.
55.5
59.1
53.9
61.5
Protein Similarity:
100
99.8
99.4
98
N.A.
98.2
95.5
N.A.
88.5
N.A.
N.A.
81
N.A.
69
70.6
69.9
73.2
P-Site Identity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
6.6
N.A.
N.A.
20
N.A.
0
0
13.3
0
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
13.3
N.A.
N.A.
40
N.A.
0
13.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
27
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.1
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
22
8
36
36
0
0
0
0
0
8
0
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% C
% Asp:
0
15
0
8
8
8
0
0
0
8
0
8
0
0
8
% D
% Glu:
8
50
0
36
15
0
15
15
15
22
8
8
8
0
8
% E
% Phe:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
8
22
8
36
8
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
22
0
8
8
8
0
8
8
8
8
15
0
8
22
0
% K
% Leu:
0
8
0
0
0
0
0
0
8
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
15
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
15
36
8
0
8
0
8
0
8
0
36
8
0
0
% P
% Gln:
0
0
8
15
0
8
8
8
0
0
0
0
0
0
0
% Q
% Arg:
36
0
0
0
0
15
8
0
36
8
0
15
0
43
22
% R
% Ser:
0
0
8
8
15
15
36
36
15
0
43
0
0
8
0
% S
% Thr:
8
0
0
0
8
0
0
0
8
0
0
8
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
8
15
8
50
0
43
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _