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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGK
All Species:
12.42
Human Site:
Y224
Identified Species:
21.03
UniProt:
Q53H12
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.62
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53H12
NP_060708.1
422
47137
Y224
A
G
V
K
V
S
K
Y
W
Y
L
G
P
L
K
Chimpanzee
Pan troglodytes
XP_001156048
422
47094
Y224
A
G
V
K
V
S
K
Y
W
Y
L
G
P
L
K
Rhesus Macaque
Macaca mulatta
XP_001083626
422
47078
Y224
A
G
V
K
V
S
K
Y
W
Y
L
G
P
L
K
Dog
Lupus familis
XP_539880
421
46699
K223
D
A
G
V
K
V
S
K
Y
W
Y
L
G
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESW4
421
46957
K223
D
A
G
V
K
V
S
K
Y
W
Y
L
G
P
L
Rat
Rattus norvegicus
NP_001120969
421
46750
K223
D
A
G
V
K
V
S
K
Y
W
Y
L
G
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515850
753
82083
K288
D
A
G
V
K
V
N
K
Y
W
Y
L
G
P
L
Chicken
Gallus gallus
XP_416354
424
47762
K226
D
A
G
V
K
V
S
K
Y
W
Y
L
G
P
L
Frog
Xenopus laevis
Q7ZYJ3
428
47944
K226
D
A
S
V
K
V
S
K
Y
W
Y
L
G
P
L
Zebra Danio
Brachydanio rerio
Q7ZW00
422
47526
Y227
V
A
T
S
I
S
K
Y
W
Y
L
G
P
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723549
408
45697
K224
L
E
D
I
D
A
A
K
D
K
Y
W
Y
F
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10123
439
49955
R232
F
R
Q
I
E
D
T
R
K
K
F
W
Y
F
S
Sea Urchin
Strong. purpuratus
XP_784956
377
42102
Q193
I
I
K
G
F
T
R
Q
V
D
V
M
S
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LRB0
763
83573
H503
L
D
T
C
S
S
T
H
A
S
T
E
P
S
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.5
91.9
N.A.
91.7
90.7
N.A.
42.9
74.5
68.9
60.4
N.A.
25.1
N.A.
22.1
33.6
Protein Similarity:
100
99.7
99.2
96.2
N.A.
95.2
94
N.A.
49.5
85.8
82.4
75.3
N.A.
44.5
N.A.
39.8
54.5
P-Site Identity:
100
100
100
0
N.A.
0
0
N.A.
0
0
0
66.6
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
13.3
N.A.
13.3
13.3
13.3
73.3
N.A.
6.6
N.A.
0
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
50
0
0
0
8
8
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
43
8
8
0
8
8
0
0
8
8
0
0
0
0
0
% D
% Glu:
0
8
0
0
8
0
0
0
0
0
0
8
0
0
8
% E
% Phe:
8
0
0
0
8
0
0
0
0
0
8
0
0
15
0
% F
% Gly:
0
22
36
8
0
0
0
0
0
0
0
29
43
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
15
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
22
43
0
29
50
8
15
0
0
0
0
29
% K
% Leu:
15
0
0
0
0
0
0
0
0
0
29
43
0
29
43
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
36
43
0
% P
% Gln:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% Q
% Arg:
0
8
0
0
0
0
8
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
8
8
36
36
0
0
8
0
0
8
8
8
% S
% Thr:
0
0
15
0
0
8
15
0
0
0
8
0
0
0
0
% T
% Val:
8
0
22
43
22
43
0
0
8
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
29
43
0
15
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
29
43
29
50
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _