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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SETMAR All Species: 8.79
Human Site: S642 Identified Species: 27.62
UniProt: Q53H47 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53H47 NP_006506.3 671 76669 S642 A F Q E F V E S Q S T D F Y A
Chimpanzee Pan troglodytes XP_526121 684 78096 S655 A F R E F V E S Q S T D F Y T
Rhesus Macaque Macaca mulatta XP_001099426 671 76517 S642 A F Q E F V K S R S T D F Y A
Dog Lupus familis XP_533755 318 35327 C290 D H G K I R K C C Y C G A K S
Cat Felis silvestris
Mouse Mus musculus Q80UJ9 309 34502 C281 K D K E K I D C S P P R K P C
Rat Rattus norvegicus Q5I0M0 315 35011 P287 D C G Q P R K P C Y C G A Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001107072 293 32317 G265 E T H V G A D G E E I P Q K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121351 342 40208 D314 V Q F F A S K D E T F F K N G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 97.6 38.7 N.A. 36.2 36.5 N.A. N.A. N.A. N.A. 23.1 N.A. N.A. 21 N.A. N.A.
Protein Similarity: 100 97.9 99.1 41.4 N.A. 39.2 39.9 N.A. N.A. N.A. N.A. 29.5 N.A. N.A. 34.1 N.A. N.A.
P-Site Identity: 100 86.6 86.6 0 N.A. 6.6 0 N.A. N.A. N.A. N.A. 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 93.3 100 20 N.A. 26.6 20 N.A. N.A. N.A. N.A. 13.3 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 38 0 0 0 13 13 0 0 0 0 0 0 25 0 25 % A
% Cys: 0 13 0 0 0 0 0 25 25 0 25 0 0 0 13 % C
% Asp: 25 13 0 0 0 0 25 13 0 0 0 38 0 0 0 % D
% Glu: 13 0 0 50 0 0 25 0 25 13 0 0 0 0 0 % E
% Phe: 0 38 13 13 38 0 0 0 0 0 13 13 38 0 0 % F
% Gly: 0 0 25 0 13 0 0 13 0 0 0 25 0 0 13 % G
% His: 0 13 13 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 13 13 0 0 0 0 13 0 0 0 0 % I
% Lys: 13 0 13 13 13 0 50 0 0 0 0 0 25 25 13 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % N
% Pro: 0 0 0 0 13 0 0 13 0 13 13 13 0 13 0 % P
% Gln: 0 13 25 13 0 0 0 0 25 0 0 0 13 13 0 % Q
% Arg: 0 0 13 0 0 25 0 0 13 0 0 13 0 0 0 % R
% Ser: 0 0 0 0 0 13 0 38 13 38 0 0 0 0 25 % S
% Thr: 0 13 0 0 0 0 0 0 0 13 38 0 0 0 13 % T
% Val: 13 0 0 13 0 38 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 25 0 0 0 38 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _