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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRMT12
All Species:
9.09
Human Site:
S180
Identified Species:
20
UniProt:
Q53H54
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53H54
NP_060426.2
448
50236
S180
L
A
K
R
G
R
V
S
P
D
G
T
R
T
P
Chimpanzee
Pan troglodytes
XP_519945
448
50116
S180
L
A
K
R
G
R
V
S
P
D
G
T
R
T
P
Rhesus Macaque
Macaca mulatta
XP_001101713
445
49992
S180
L
A
K
R
G
R
V
S
P
D
G
T
R
T
P
Dog
Lupus familis
XP_851753
439
49172
D173
K
R
G
R
V
S
P
D
G
T
R
T
P
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG71
446
50281
D172
K
R
G
R
V
L
P
D
G
T
R
T
P
S
V
Rat
Rattus norvegicus
Q4V8B8
437
49368
D172
K
R
G
R
V
L
P
D
G
T
R
T
P
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517753
421
46670
A175
L
A
K
R
G
R
V
A
P
G
G
T
R
T
P
Chicken
Gallus gallus
XP_420244
552
60050
L288
L
A
K
R
G
R
V
L
P
D
K
M
C
S
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q0P466
408
45512
E192
I
D
N
H
I
R
Y
E
F
D
V
T
K
C
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798254
334
36592
I121
A
C
A
A
L
N
P
I
T
G
G
V
L
H
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04235
462
52708
Q204
L
R
R
P
F
N
I
Q
P
L
Y
G
K
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.2
85.2
N.A.
79.2
80.5
N.A.
62.9
47.4
N.A.
47
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
100
99.5
97
89.9
N.A.
86.1
86.8
N.A.
72.9
56.1
N.A.
62.9
N.A.
N.A.
N.A.
N.A.
33.9
P-Site Identity:
100
100
100
13.3
N.A.
13.3
20
N.A.
86.6
66.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
20
20
N.A.
93.3
73.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
46
10
10
0
0
0
10
0
0
0
0
0
10
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
10
10
0
% C
% Asp:
0
10
0
0
0
0
0
28
0
46
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
28
0
46
0
0
0
28
19
46
10
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
0
0
10
0
10
10
0
0
0
0
0
0
19
% I
% Lys:
28
0
46
0
0
0
0
0
0
0
10
0
19
0
0
% K
% Leu:
55
0
0
0
10
19
0
10
0
10
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% M
% Asn:
0
0
10
0
0
19
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
37
0
55
0
0
0
28
0
46
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
37
10
73
0
55
0
0
0
0
28
0
37
0
0
% R
% Ser:
0
0
0
0
0
10
0
28
0
0
0
0
0
19
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
28
0
73
0
46
0
% T
% Val:
0
0
0
0
28
0
46
0
0
0
10
10
0
0
28
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _