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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRMT12 All Species: 21.52
Human Site: S300 Identified Species: 47.33
UniProt: Q53H54 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53H54 NP_060426.2 448 50236 S300 D N R K L K L S N I A D R V I
Chimpanzee Pan troglodytes XP_519945 448 50116 S300 D N R K L K L S N I A D R V I
Rhesus Macaque Macaca mulatta XP_001101713 445 49992 S300 D N R K L K L S N I A D R V I
Dog Lupus familis XP_851753 439 49172 S291 D N R K L K L S N I A D R V N
Cat Felis silvestris
Mouse Mus musculus Q8BG71 446 50281 S290 D N R K L K L S D I A D R V N
Rat Rattus norvegicus Q4V8B8 437 49368 S290 D N R K L K L S N T A D R V N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517753 421 46670 N276 L R R N L E L N G V A D R C Q
Chicken Gallus gallus XP_420244 552 60050 R408 D S R Q L Q L R D V A D R V N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q0P466 408 45512 H273 V S N R C T V H Q G D N R Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798254 334 36592 D202 F T P V L A E D M L P A D S M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04235 462 52708 A320 G L K R G L K A N G F N K S G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 96.2 85.2 N.A. 79.2 80.5 N.A. 62.9 47.4 N.A. 47 N.A. N.A. N.A. N.A. 20.5
Protein Similarity: 100 99.5 97 89.9 N.A. 86.1 86.8 N.A. 72.9 56.1 N.A. 62.9 N.A. N.A. N.A. N.A. 33.9
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 40 53.3 N.A. 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 86.6 N.A. 60 86.6 N.A. 40 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 10 0 0 73 10 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 64 0 0 0 0 0 0 10 19 0 10 73 10 0 0 % D
% Glu: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 10 0 0 0 10 0 0 0 10 19 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 46 0 0 0 0 28 % I
% Lys: 0 0 10 55 0 55 10 0 0 0 0 0 10 0 0 % K
% Leu: 10 10 0 0 82 10 73 0 0 10 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % M
% Asn: 0 55 10 10 0 0 0 10 55 0 0 19 0 0 37 % N
% Pro: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 10 0 10 0 0 10 0 0 0 0 10 10 % Q
% Arg: 0 10 73 19 0 0 0 10 0 0 0 0 82 0 0 % R
% Ser: 0 19 0 0 0 0 0 55 0 0 0 0 0 19 0 % S
% Thr: 0 10 0 0 0 10 0 0 0 10 0 0 0 0 0 % T
% Val: 10 0 0 10 0 0 10 0 0 19 0 0 0 64 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _