KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LACTB2
All Species:
26.97
Human Site:
Y121
Identified Species:
49.44
UniProt:
Q53H82
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53H82
NP_057111.1
288
32806
Y121
I
G
N
G
E
Q
Q
Y
V
Y
L
K
D
G
D
Chimpanzee
Pan troglodytes
XP_001164196
288
32801
Y121
I
G
N
G
E
Q
Q
Y
V
Y
L
K
D
G
D
Rhesus Macaque
Macaca mulatta
XP_001083676
262
29390
E111
L
P
R
N
P
Q
R
E
E
I
I
G
N
G
E
Dog
Lupus familis
XP_544119
288
32625
Y121
I
G
D
G
T
Q
Q
Y
V
Y
L
Q
D
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99KR3
288
32736
F121
I
G
N
G
E
Q
Q
F
I
Y
I
E
N
G
D
Rat
Rattus norvegicus
Q561R9
288
32466
Y121
I
G
S
G
E
Q
Q
Y
V
Y
I
E
D
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517368
208
23618
A59
E
N
I
G
H
G
T
A
Y
V
I
K
K
L
P
Chicken
Gallus gallus
XP_418292
288
32408
Y121
I
G
D
G
G
H
K
Y
L
Y
L
K
D
G
D
Frog
Xenopus laevis
Q5XGR8
287
32401
Y120
E
V
I
A
D
H
K
Y
N
Y
L
K
D
G
D
Zebra Danio
Brachydanio rerio
Q6NYF0
289
32385
Y121
I
G
D
D
K
K
K
Y
S
Y
L
N
D
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLS9
292
32715
L121
E
I
P
T
D
I
K
L
H
P
L
A
H
N
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95Q18
295
33084
F117
K
D
E
G
V
E
R
F
H
Y
V
D
D
G
F
Sea Urchin
Strong. purpuratus
XP_785886
289
32543
Y121
I
S
G
G
K
L
K
Y
N
Y
L
Q
D
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
78.4
88.1
N.A.
84
82.9
N.A.
55.2
73.2
71.1
66
N.A.
45.8
N.A.
46.4
55.7
Protein Similarity:
100
100
81.9
94.4
N.A.
93.4
93.7
N.A.
66.3
86.1
82.9
80.9
N.A.
63.7
N.A.
66
72.6
P-Site Identity:
100
100
13.3
80
N.A.
66.6
80
N.A.
13.3
66.6
46.6
53.3
N.A.
6.6
N.A.
26.6
46.6
P-Site Similarity:
100
100
46.6
93.3
N.A.
100
100
N.A.
20
86.6
60
80
N.A.
20
N.A.
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
8
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
24
8
16
0
0
0
0
0
0
8
70
0
62
% D
% Glu:
24
0
8
0
31
8
0
8
8
0
0
16
0
0
16
% E
% Phe:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
8
% F
% Gly:
0
54
8
70
8
8
0
0
0
0
0
8
0
85
0
% G
% His:
0
0
0
0
8
16
0
0
16
0
0
0
8
0
0
% H
% Ile:
62
8
16
0
0
8
0
0
8
8
31
0
0
0
0
% I
% Lys:
8
0
0
0
16
8
39
0
0
0
0
39
8
0
0
% K
% Leu:
8
0
0
0
0
8
0
8
8
0
62
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
24
8
0
0
0
0
16
0
0
8
16
8
0
% N
% Pro:
0
8
8
0
8
0
0
0
0
8
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
47
39
0
0
0
0
16
0
0
8
% Q
% Arg:
0
0
8
0
0
0
16
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
0
0
0
0
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
8
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
8
0
0
0
31
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
8
77
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _