KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYCRL
All Species:
26.06
Human Site:
S232
Identified Species:
40.95
UniProt:
Q53H96
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53H96
NP_075566.2
274
28649
S232
Q
H
P
A
Q
L
R
S
D
V
C
T
P
G
G
Chimpanzee
Pan troglodytes
XP_528256
274
28645
S232
Q
H
P
A
Q
L
R
S
D
V
C
T
P
G
G
Rhesus Macaque
Macaca mulatta
XP_001097787
532
55678
S490
Q
H
P
A
Q
L
R
S
D
V
C
T
P
G
G
Dog
Lupus familis
XP_539200
288
29923
T246
Q
H
P
A
Q
L
R
T
D
V
C
T
P
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCC4
274
28703
T232
K
H
P
A
Q
L
R
T
D
V
L
T
P
A
G
Rat
Rattus norvegicus
Q5PQJ6
274
28860
T232
K
H
P
A
Q
L
R
T
D
V
L
T
P
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518843
344
36720
T302
K
H
P
A
Q
L
R
T
D
V
C
T
P
G
G
Chicken
Gallus gallus
XP_418406
278
29308
G236
E
H
P
A
K
L
R
G
D
V
C
T
P
G
G
Frog
Xenopus laevis
A1L2Q8
274
28856
A232
E
H
P
A
S
L
R
A
D
V
C
T
P
G
G
Zebra Danio
Brachydanio rerio
Q5SPD7
288
29903
A242
K
L
P
A
E
L
K
A
E
V
C
T
P
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20848
299
32038
D254
Q
H
F
G
S
L
K
D
M
V
C
S
P
G
G
Sea Urchin
Strong. purpuratus
XP_788839
276
28973
D227
K
H
P
S
Q
L
K
D
D
V
C
S
P
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P54904
276
28606
D234
K
H
P
G
V
L
K
D
D
V
T
S
P
G
G
Baker's Yeast
Sacchar. cerevisiae
P32263
286
30113
H242
A
H
P
S
V
L
K
H
Q
V
C
T
P
G
G
Red Bread Mold
Neurospora crassa
Q12641
332
34196
E280
E
H
P
A
I
L
R
E
K
V
S
T
P
G
G
Conservation
Percent
Protein Identity:
100
99.6
50.1
82.9
N.A.
82.1
82.4
N.A.
59
59.3
58
52.7
N.A.
N.A.
N.A.
31.7
44.5
Protein Similarity:
100
99.6
51.1
88.1
N.A.
90.5
90.1
N.A.
68.9
72.3
77.7
72.2
N.A.
N.A.
N.A.
50.1
65.9
P-Site Identity:
100
100
100
93.3
N.A.
73.3
73.3
N.A.
86.6
80
80
60
N.A.
N.A.
N.A.
53.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
100
93.3
93.3
93.3
N.A.
N.A.
N.A.
66.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.1
30
30.4
Protein Similarity:
N.A.
N.A.
N.A.
59
47.9
46.6
P-Site Identity:
N.A.
N.A.
N.A.
53.3
60
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
73.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
74
0
0
0
14
0
0
0
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
74
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
20
74
0
0
0
0
0
0
% D
% Glu:
20
0
0
0
7
0
0
7
7
0
0
0
0
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
14
0
0
0
7
0
0
0
0
0
87
100
% G
% His:
0
94
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
40
0
0
0
7
0
34
0
7
0
0
0
0
0
0
% K
% Leu:
0
7
0
0
0
100
0
0
0
0
14
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
94
0
0
0
0
0
0
0
0
0
100
0
0
% P
% Gln:
34
0
0
0
54
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
14
14
0
0
20
0
0
7
20
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
27
0
0
7
80
0
0
0
% T
% Val:
0
0
0
0
14
0
0
0
0
100
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _