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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYCRL
All Species:
37.88
Human Site:
S61
Identified Species:
59.52
UniProt:
Q53H96
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53H96
NP_075566.2
274
28649
S61
L
G
C
R
T
T
H
S
N
Q
E
V
L
Q
S
Chimpanzee
Pan troglodytes
XP_528256
274
28645
S61
L
G
C
R
T
T
H
S
N
Q
E
V
L
Q
S
Rhesus Macaque
Macaca mulatta
XP_001097787
532
55678
S319
L
G
C
Q
T
T
H
S
N
Q
E
V
L
Q
S
Dog
Lupus familis
XP_539200
288
29923
S75
L
G
C
Q
T
T
H
S
N
Q
E
V
L
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCC4
274
28703
S61
L
G
C
Q
T
T
H
S
N
H
E
V
L
Q
N
Rat
Rattus norvegicus
Q5PQJ6
274
28860
S61
L
G
C
Q
T
T
H
S
N
H
E
V
L
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518843
344
36720
S131
L
G
C
R
T
T
H
S
N
T
E
V
L
T
S
Chicken
Gallus gallus
XP_418406
278
29308
C65
W
G
C
R
T
T
H
C
N
L
E
V
L
Q
E
Frog
Xenopus laevis
A1L2Q8
274
28856
D61
R
G
C
C
T
S
H
D
N
R
S
V
V
S
N
Zebra Danio
Brachydanio rerio
Q5SPD7
288
29903
S71
K
G
V
S
V
T
H
S
N
H
E
V
V
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20848
299
32038
T67
L
G
Y
K
N
V
F
T
N
T
L
E
M
L
E
Sea Urchin
Strong. purpuratus
XP_788839
276
28973
S56
L
G
A
K
T
T
S
S
N
R
E
I
L
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P54904
276
28606
T64
F
G
V
N
V
F
S
T
S
E
E
V
V
K
E
Baker's Yeast
Sacchar. cerevisiae
P32263
286
30113
N76
V
E
S
T
Y
G
H
N
V
S
A
V
E
E
A
Red Bread Mold
Neurospora crassa
Q12641
332
34196
S90
L
R
V
L
Q
S
T
S
N
V
S
A
A
A
E
Conservation
Percent
Protein Identity:
100
99.6
50.1
82.9
N.A.
82.1
82.4
N.A.
59
59.3
58
52.7
N.A.
N.A.
N.A.
31.7
44.5
Protein Similarity:
100
99.6
51.1
88.1
N.A.
90.5
90.1
N.A.
68.9
72.3
77.7
72.2
N.A.
N.A.
N.A.
50.1
65.9
P-Site Identity:
100
100
93.3
93.3
N.A.
80
80
N.A.
86.6
73.3
40
46.6
N.A.
N.A.
N.A.
20
53.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
73.3
66.6
53.3
N.A.
N.A.
N.A.
40
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.1
30
30.4
Protein Similarity:
N.A.
N.A.
N.A.
59
47.9
46.6
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
0
0
7
7
7
7
7
% A
% Cys:
0
0
60
7
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% D
% Glu:
0
7
0
0
0
0
0
0
0
7
74
7
7
14
27
% E
% Phe:
7
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
87
0
0
0
7
0
0
0
0
0
0
0
7
7
% G
% His:
0
0
0
0
0
0
74
0
0
20
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
7
0
0
14
0
0
0
0
0
0
0
0
0
7
0
% K
% Leu:
67
0
0
7
0
0
0
0
0
7
7
0
60
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
7
7
0
0
7
87
0
0
0
0
0
20
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
27
7
0
0
0
0
27
0
0
0
47
0
% Q
% Arg:
7
7
0
27
0
0
0
0
0
14
0
0
0
0
0
% R
% Ser:
0
0
7
7
0
14
14
67
7
7
14
0
0
7
34
% S
% Thr:
0
0
0
7
67
67
7
14
0
14
0
0
0
7
7
% T
% Val:
7
0
20
0
14
7
0
0
7
7
0
80
20
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _